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Saliva stagnates and forms a mucus plug behind the stricture during sleep when the salivary output of the parotid is reduced. Then, when salivary secretion is stimulated, the mucus plug becomes stuck in the stricture. [1] The backlog of saliva behind the blockage causes the swelling, and the increased pressure inside the gland causes the pain.
Sialolithiasis (also termed salivary calculi, [1] or salivary stones) [1] is a crystallopathy where a calcified mass or sialolith forms within a salivary gland, usually in the duct of the submandibular gland (also termed "Wharton's duct"). Less commonly the parotid gland or rarely the sublingual gland or a minor salivary gland may develop ...
The blockage may be from a salivary stone, a mucous plug, or, more rarely, by a tumor, usually benign. Salivary stones (also called sialolithiasis, or salivary duct calculus) are mainly made of calcium, but do not indicate any kind of calcium disorder. [7] Other causes can be duct stricture (narrowing of the duct), infection or injury.
Ectopic salivary gland tissue; Stafne defect - an uncommon condition which some consider to be an anatomic variant rather than a true disease. It is thought to be created by an ectopic portion of salivary gland tissue which causes the bone of the mandible to remodel around the tissue, creating an apparent cyst like
The two parotid glands are major salivary glands wrapped around the mandibular ramus in humans. [6] These are largest of the salivary glands, secreting saliva to facilitate mastication and swallowing, and amylase to begin the digestion of starches. [7] It is the serous type of gland which secretes alpha-amylase (also known as ptyalin). [8]
Sialadenitis (sialoadenitis) is inflammation of salivary glands, usually the major ones, the most common being the parotid gland, followed by submandibular and sublingual glands. [1] It should not be confused with sialadenosis (sialosis) which is a non-inflammatory enlargement of the major salivary glands. [2]
An unstimulated salivary flow rate of 0.1 to 0.2 ml/min and a stimulated flow rate of 0.7 ml/min or less is considered to be abnormally low flow rates indicative of salivary gland hypofunction. [61] Unstimulated saliva production reduces by 40 to 70% between the age of 20 and 80 years, but stimulated saliva production is not affected. [62]
The submandibular duct (also Wharton's duct or historically submaxillary duct) is one of the salivary excretory ducts. It is about 5 cm long, and its wall is much thinner than that of the parotid duct. It drains saliva from each bilateral submandibular gland and sublingual gland to the sublingual caruncle in the floor of the mouth.