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The definition of the condition includes the requirement that the duodenal histological appearances are otherwise unremarkable, specifically with normal villous architecture. [2] In coeliac disease (also known as gluten-sensitive enteropathy), duodenal lymphocytosis is found in untreated or partially treated cases. This is the least severe type ...
Villous blunting; Crypt hypertrophy; Villous fusion; Mucosal inflammation; The key histological features are villous flattening, crypt hyperplasia and inflammation in the epithelium and lamina propria. [34] [40] However, this procedure is considered too invasive, complex and expensive to be implemented as standard of care. [2]
Known causes of duodenitis include: [2] Helicobacter pylori infection; Coeliac disease; Bacterial infection; Viral infection; NSAIDs; Autoimmune diseases (i.e. Crohn's disease) Duodenal lymphocytosis; Idiopathic
Histopathological features include small bowel villous changes such as atrophy and blunting, typically prominent in the proximal bowel. [12] Occasionally crypt abscesses are also seen. [ 50 ] The crypt epithelium may contain apoptotic bodies and lymphocytic infiltration, with comparatively little surface lymphocytosis (less than 40 lymphocytes ...
After surgery involving the stomach and duodenum (most commonly with Billroth II antrectomy), a blind loop may be formed, leading to stasis of flow of intestinal contents. This can cause overgrowth, and is termed blind loop syndrome. [23] Systemic or metabolic disorders may lead to conditions allowing bacterial overgrowth as well.
Biopsy of small bowel showing coeliac disease manifested by blunting of villi, crypt hyperplasia, and lymphocyte infiltration of crypts. OGD to detect duodenal pathology and obtain D2 biopsy (for coeliac disease, tropical sprue, Whipple's disease, abetalipoproteinaemia etc.) Enteroscopy for enteropathy and jejunal aspirate and culture for ...
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Lymphangiectasia, also known as "lymphangiectasis", [1] is a pathologic dilation of lymph vessels. [2] When it occurs in the intestines it is known as intestinal lymphangiectasia, colloquially recognized as Waldmann's disease in cases where there is no secondary cause. [3]