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Glands of Zeis are unilobar sebaceous glands located on the margin of the eyelid.The glands of Zeis service the eyelash.These glands produce an oily substance that is issued through the excretory ducts of the sebaceous lobule into the middle portion of the hair follicle.
Moll's gland, also known as the gland of Moll or ciliary gland, is a modified apocrine sweat gland that is found on the margin of the eyelid. They are next to the base of the eyelashes, and anterior to the meibomian glands within the distal eyelid margin. These glands are relatively large and tubular-shaped.
Hidrocystoma (also known as cystadenoma, [1] a Moll's gland cyst, [1] and a sudoriferous cyst [1]) is an adenoma of the sweat glands. [2]: 787 Hidrocystomas are cysts of sweat ducts, usually on the eyelids. [3]: 664 They are not tumours (a similar-sounding lesion called hidroadenoma is a benign tumour).
The cysts can be removed via excision, though conventional cyst excision techniques have proven impractical, and a specialized regimen is required. [5] Cryotherapy and electrodessication may also be tried, but since it is a genetic disorder all the modalities have very little effect. Individual cysts can be removed surgically.
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Ciaccio's glands are named after Italian anatomist Giuseppe Vincenzo Ciaccio (1824–1901), who described these glands in 1874. They are sometimes called "Wolfring's glands" after Polish ophthalmologist Emilj von Wolfring (1832-1906), who described them during the same time period as did Ciaccio.
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[12] [13] Besides leading to dry eyes, the obstructions can be degraded by bacterial lipases, resulting in the formation of free fatty acids, which irritate the eyes and sometimes cause punctate keratopathy. Meibomian gland dysfunction is more often seen in women and is regarded as the main cause of dry eye disease.