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  2. Rivaroxaban - Wikipedia

    en.wikipedia.org/wiki/Rivaroxaban

    Rivaroxaban was patented in 2007 and approved for medical use in the United States in 2011. [10] It is available as a generic medication. [11] It is on the World Health Organization's List of Essential Medicines. [12] In 2022, it was the 90th most commonly prescribed medication in the United States, with more than 7 million prescriptions. [13] [14]

  3. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Antistasin, the first discovered naturally occurring direct Xa inhibitor Rivaroxaban, the first synthetic direct Xa inhibitor marketed as a drug Prior to the introduction of direct factor Xa inhibitors, vitamin K antagonists such as warfarin were the only oral anticoagulants for over 60 years, and together with heparin have been the main blood ...

  4. List of therapeutic monoclonal antibodies - Wikipedia

    en.wikipedia.org/wiki/List_of_therapeutic...

    This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.

  5. J&J Wins Blockbuster Approval to Market Xarelto for Stroke ...

    www.aol.com/news/2011-11-05-jj-wins-blockbuster...

    The FDA has given Johnson & Johnson (NYS: JNJ) the green light to market Xarelto to prevent stroke among patients suffering from atrial fibrillation -- opening up a blockbuster market involving ...

  6. Novartis's Multiple Sclerosis Pill, a Likely Blockbuster ...

    www.aol.com/2010/09/22/novartis-multiple...

    It took nine months since Novartis (NVS) published results from a late-stage study of its multiple sclerosis pill, but the Swiss pharmaceutical finally announced Wednesday that the U.S. Food and ...

  7. AstraZeneca's Brilinta Fails to Win FDA Approval - AOL

    www.aol.com/news/2010-12-17-astrazenecas...

    AstraZeneca (AZN) announced that it failed to win the approval of the U.S. Food and Drug Administration for its heart drug Brilinta, a blood-thinner that the company -- facing a severe patent ...

  8. List of largest selling pharmaceutical products - Wikipedia

    en.wikipedia.org/wiki/List_of_largest_selling...

    Drug Main indication Trade name 2015 2016 ... rivaroxaban: anticoagulant: Xarelto 6589 6234 12 ... First Approval Date Patent Expiration Date [6] [7] 1:

  9. List of antiretroviral fixed-dose combinations - Wikipedia

    en.wikipedia.org/wiki/List_of_antiretroviral...

    (not approved) (many companies) Yes Generics, e.g., Duovir-N: lamivudine zidovudine: nevirapine (not approved) (many companies) Yes Truvada: emtricitabine tenofovir disoproxil: August 2, 2004 Gilead Sciences: No Atripla: emtricitabine tenofovir disoproxil efavirenz: July 12, 2006 Gilead Sciences Bristol-Myers Squibb: Yes Complera (US) Eviplera ...