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A separate study, published in the Journal of the American Academy of Dermatology looked at the effects of topical minoxidil in men with pattern hair loss over a total treatment period of 48 weeks.
The risks of using high-strength minoxidil include an increased likelihood of side effects. When using it as a topical solution, side effects of minoxidil may include: Skin irritation. Itching ...
Minoxidil (brand name Rogaine®) is a non-prescription topical medication that promotes hair growth and regrowth by restarting the growth phase in dormant hair follicles.
Minoxidil is a medication used for the treatment of high blood pressure and pattern hair loss. [5] [6] [7] It is an antihypertensive and a vasodilator. [10] It is available as a generic medication by prescription in oral tablet form and over-the-counter as a topical liquid or foam. [8] [9] [11] [12]
Topical corticosteroids frequently fail to enter the skin deeply enough to affect the hair bulbs, which are the treatment target, [20] and small lesions typically also regrow spontaneously. Oral corticosteroids may decrease the hair loss, but only for the period during which they are taken, and these medications can cause serious side effects. [20]
Minoxidil sulfate is formed from minoxidil via sulfotransferase enzymes, with the predominant enzyme responsible, at least in hair follicles, being SULT1A1. [ 1 ] [ 2 ] Minoxidil sulfate acts as a potassium channel opener , among other actions, and has vasodilating , hypotensive , and trichogenic or hypertrichotic (hair growth-promoting) effects.
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