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  2. Hormone receptor positive breast tumor - Wikipedia

    en.wikipedia.org/wiki/Hormone_receptor_positive...

    ER-positive is one of the Receptor statuses identified in the classification of breast cancer.Receptor status was traditionally considered by reviewing each individual receptor (ER, PR, her2) in turn, but newer approaches look at these together, along with the tumor grade, to categorize breast cancer into several conceptual molecular classes [1] that have different prognoses [2] and may have ...

  3. Breast cancer - Wikipedia

    en.wikipedia.org/wiki/Breast_cancer

    This is an accepted version of this page This is the latest accepted revision, reviewed on 14 January 2025. Cancer that originates in mammary glands Medical condition Breast cancer An illustration of breast cancer Specialty Surgical Oncology Symptoms A lump in a breast, a change in breast shape, dimpling of the skin, fluid from the nipple, a newly inverted nipple, a red scaly patch of skin on ...

  4. Breast cancer classification - Wikipedia

    en.wikipedia.org/wiki/Breast_cancer_classification

    Staging of breast cancer is one aspect of breast cancer classification that assists in making appropriate treatment choices, when considered along with other classification aspects such as estrogen receptor and progesterone receptor levels in the cancer tissue, the human epidermal growth factor receptor 2 status, menopausal status, and the ...

  5. Combination therapy shows promise against triple-negative ...

    www.aol.com/combination-therapy-shows-promise...

    A combination of two types of therapeutic agents selectively killed breast cancer cells in ... and has a worse prognosis than other breast ... do not respond to hormone therapy or anti-HER2 drugs ...

  6. What is stage I triple-positive breast cancer? - AOL

    www.aol.com/lifestyle/office-star-jenna-fischer...

    When a tumor is “triple positive,” that means that its growth is fueled by both estrogen and progesterone hormones, as well as a protein called human epidermal growth factor receptor 2 (HER2 ...

  7. Endocrine therapy resistance in breast cancer - Wikipedia

    en.wikipedia.org/wiki/Endocrine_therapy...

    The receptor status of a cancer is assessed for all breast cancers as it has important implications on prognosis of the patient. It also dictates the treatment given: cancers that do express ER are likely to respond to endocrine therapy, but this type of therapy will have no effect on triple-negative breast cancers.

  8. Triple-negative breast cancer - Wikipedia

    en.wikipedia.org/wiki/Triple-negative_breast_cancer

    Triple-negative breast cancer (TNBC) is any breast cancer that either lacks or shows low levels of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) overexpression and/or gene amplification (i.e. the tumor is negative on all three tests giving the name triple-negative). [1]

  9. Breast cancer management - Wikipedia

    en.wikipedia.org/wiki/Breast_cancer_management

    Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.

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