Ads
related to: huntington's disease progression chart- Download Discussion Guide
Find ways to start a conversation
with your doctor about HD chorea.
- See Their Stories
Read stories from inspiring
individuals that live with HD.
- Recognizing HD Symptoms
Learn More About Symptoms and
Signs of Huntington's HD Chorea.
- See FAQs
Discover the most frequently asked
questions about HD chorea.
- Download Discussion Guide
Search results
Results from the WOW.Com Content Network
Huntington's disease (HD), also known as Huntington's chorea, is an incurable neurodegenerative disease [7] that is mostly inherited. [8] The earliest symptoms are often subtle problems with mood or mental/psychiatric abilities. [9] [1] A general lack of coordination and an unsteady gait often follow. [2]
Each successive generation in a Huntington's-affected family may add additional CAG repeats, and the higher the number of repeats, the more severe the disease and the earlier its onset. [21] As a result, families that have had Huntington's for many generations show an earlier age of disease onset and faster disease progression. [21]
Huntington's disease presents itself later in life even though the proteins that cause the disease works towards manifestation from their early stages in the humans affected by the proteins. [35] Along with being a neurodegenerative disorder, HD has links to problems with neurodevelopment.
Huntington's disease is a neurodegenerative disease caused by mutations in a single gene HTT, that encodes for huntingtin protein. Symptoms include cognitive impairment and this usually declines further into dementia. [83] The first main symptoms of Huntington's disease often include: difficulty concentrating; memory lapses
This is the case for Huntington's disease, where the trinucleotide repeat encodes a long stretch of glutamine residues. When the repeat is present in an untranslated region, it could affect the expression of the gene in which the repeat is found (ex. fragile X ) or many genes through a dominant negative effect (ex. myotonic dystrophy ).
HOPES Logo. The Huntington's disease Outreach Project for Education at Stanford (HOPES) is a student-run project at Stanford University dedicated to making scientific information about Huntington's disease (HD) more readily accessible to patients and the public.
Ads
related to: huntington's disease progression chart