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LAM antigen is a lipopolysaccharide present in mycobacterial cell walls, which is released from metabolically active or degenerating bacterial cells and appears to be present only in people with active TB disease. Urine-based testing have advantages over sputum-based testing because urine is easy to collect and store, and lacks the infection ...
Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. [1] [2] First discovered in 1882 by Robert Koch, M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid.
Typically, most white blood cells (WBCs) in urine are neutrophils. They are round, larger than RBCs, possess a cell nucleus, and have a granular appearance. A few white blood cells can normally be found in the urine of healthy individuals; females tend to have slightly more than males.
Effective TB treatment is difficult, due to the unusual structure and chemical composition of the mycobacterial cell wall, which hinders the entry of drugs and makes many antibiotics ineffective. [137] Active TB is best treated with combinations of several antibiotics to reduce the risk of the bacteria developing antibiotic resistance. [14]
A negative dipstick test does not exclude bacteriuria, as not all bacteria which can colonise the urinary tract are nitrate-reducing. The leukocyte esterase test indirectly detects the presence of leukocytes (white blood cells) in urine which can be associated with a urinary tract infection. In the elderly, the leukocyte esterase test is often ...
Kay Granger’s spox denies claims that she’s in a memory care facility. A spokesperson for the retiring rep, Valerie Nelson, also said Kay Granger is not in a memory care unit, releasing a ...
Sydney Sweeney is living her best life in Florida (where she owns a $13.5 million mansion on the water), and just dropped a picture of herself lounging on a jet ski.
TB also gets to nearby hilar lymph nodes, either carried over by immune cells through the lymph or by direct extension of the Ghon focus infection and causes caseation there as well, and together, this caseating tissue and associated lymph node make up the characteristic “Ghon complex”.