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  2. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart can be a useful tool, but the user must take care to correct for all relevant variables such as route of administration, cross tolerance, half-life and the bioavailability of a drug. [5] For example, the narcotic levorphanol is 4–8 times stronger than morphine, but also has a much longer half-life. Simply switching the ...

  3. Dimenhydrinate - Wikipedia

    en.wikipedia.org/wiki/Dimenhydrinate

    Diphenhydramine is the primary constituent of dimen­hydrinate and dictates the primary effect. The main differences relative to pure diphen­hydramine are a lower potency due to being combined with 8-chloro­theo­phylline (by weight, dimen­hydrinate is between 53% and 55.5% diphen­hydramine) [10] and the fact that the stimulant properties of 8-chloro­theo­phylline help reduce the side ...

  4. Metoprolol - Wikipedia

    en.wikipedia.org/wiki/Metoprolol

    Metoprolol is a beta blocker, or an antagonist of the β-adrenergic receptors. It is specifically a selective antagonist of the β 1-adrenergic receptor and has no intrinsic sympathomimetic activity. [37] Metoprolol exerts its effects by blocking the action of certain neurotransmitters, specifically adrenaline and noradrenaline.

  5. Maps and images reveal scale of LA wildfire devastation - AOL

    www.aol.com/los-angeles-wildfires-maps-180658327...

    A combination of an exceptionally dry period - downtown Los Angeles has only received 0.16 inches (0.4cm) of rain since October - and powerful offshore gusts known as the Santa Ana winds have ...

  6. Man United secures stunning late 2-1 comeback win against Man ...

    www.aol.com/ismaila-sarrs-double-helps-crystal...

    Amad Diallo struck a 90th-minute winner as Manchester United staged a stunning late comeback to beat Manchester City 2-1 in the Premier League on Sunday. Four-time defending champion City led the ...

  7. Diphenhydramine - Wikipedia

    en.wikipedia.org/wiki/Diphenhydramine

    It is expected that low doses of diphenhydramine taken occasionally will cause no adverse effects in breastfed infants. Large doses and long-term use may affect the baby or reduce breast milk supply, especially when combined with sympathomimetic drugs , such as pseudoephedrine, or before the establishment of lactation.

  8. Explainer-Who are the immigrants who could be targeted in ...

    www.aol.com/news/explainer-immigrants-could...

    President-elect Donald Trump plans to launch a mass deportation operation targeting millions of immigrants living in the U.S. illegally and with temporary protections once he takes office on Jan ...

  9. Xanomeline - Wikipedia

    en.wikipedia.org/wiki/Xanomeline

    Xanomeline is an agonist that primarily targets the muscarinic acetylcholine receptor family of five muscarinic receptor subtypes, which are designated M 1-M 5. [2] While it binds with near identical affinity to all five of the muscarinic receptor subtypes as measured by displacement of a muscarinic radioligand, the preponderance of evidence suggests that xanomeline acts preferentially in the ...

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