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  2. Metoprolol - Wikipedia

    en.wikipedia.org/wiki/Metoprolol

    Metoprolol is classified as a moderately lipophilic beta blocker. [37] More lipophilic beta blockers tend to cross the blood–brain barrier more readily, with greater potential for effects in the central nervous system as well as associated neuropsychiatric side effects. [37] Metoprolol binds mainly to human serum albumin with an unbound ...

  3. Modified-release dosage - Wikipedia

    en.wikipedia.org/wiki/Modified-release_dosage

    Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release [ER, XR, XL] dosage) or to a specific target in the body (targeted-release dosage). [1]

  4. Talk:Metoprolol - Wikipedia

    en.wikipedia.org/wiki/Talk:Metoprolol

    A distinction should be made. --Tarcieri 19:59, 5 February 2006 (UTC) It currently says that Toprol XL is "metoprolol succinate, the sustained release formulation". Does this mean that the succinate salt is inherently longer-lasting (like polistirex or something), or is the sustained release mechanical, like most?

  5. Renin inhibitor - Wikipedia

    en.wikipedia.org/wiki/Renin_inhibitor

    Renin is highly selective for its only naturally occurring substrate which is angiotensinogen, and the incidence of unwanted side effects with a renin inhibitor is infrequent. [26] and similar to angiotensin II receptor antagonists. [27] Ang II also functions within the RAAS as a negative feedback to suppress further release of renin.

  6. ACE inhibitor - Wikipedia

    en.wikipedia.org/wiki/ACE_inhibitor

    Angiotensin-converting-enzyme inhibitors (ACE inhibitors) are a class of medication used primarily for the treatment of high blood pressure and heart failure. [1] [2] This class of medicine works by causing relaxation of blood vessels as well as a decrease in blood volume, which leads to lower blood pressure and decreased oxygen demand from the heart.

  7. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

    www.aol.com/cialis-side-effects-expect-avoid...

    This side effect was most common in guys who took 10 to 20 milligrams of Cialis a day. Tadalafil Side Effects Long-Term There are no known long-term side effects of tadalafil.

  8. Discovery and development of beta-blockers - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    It has been shown that the side chains of aryloxypropanolamine can adopt a conformation that puts the hydroxyl and amine groups in more or less the same position as with beta blocker that do not have this group as a part of the side chain. [2] After the release of propranolol, relative lipophilicity of β-blockers as a significant factor in ...

  9. 6 Signs Wellbutrin is Right for Your Depression Symptoms - AOL

    www.aol.com/6-signs-wellbutrin-depression...

    Wellbutrin is sold as a sustained-release or extended-release tablet. Your mental health provider may recommend taking it one to four times each day, based on your needs and the dosage form of ...

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