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Ubiquitin is a small (8.6 kDa) regulatory protein found in most tissues of eukaryotic organisms, i.e., it is found ubiquitously. It was discovered in 1975 [1] by Gideon Goldstein and further characterized throughout the late 1970s and 1980s. [2] Four genes in the human genome code for ubiquitin: UBB, UBC, UBA52 and RPS27A. [3]
In molecular biology, the mass of macromolecules is referred to as their molecular weight and is expressed in kDa, although the numerical value is often approximate and representative of an average. The terms "molecular mass", "molecular weight", and "molar mass" may be used interchangeably in less formal contexts where unit- and quantity ...
P-gp is a 170 kDa transmembrane glycoprotein, which includes 10–15 kDa of N-terminal glycosylation.The N-terminal half of the protein contains six transmembrane helixes, followed by a large cytoplasmic domain with an ATP-binding site, and then a second section with six transmembrane helixes and an ATP-binding domain that shows over 65% of amino acid similarity with the first half of the ...
The dalton or unified atomic mass unit (symbols: Da or u, respectively) is a unit of mass defined as 1 / 12 of the mass of an unbound neutral atom of carbon-12 in its nuclear and electronic ground state and at rest.
The average size of a protein increases from Archaea to Bacteria to Eukaryote (283, 311, 438 residues and 31, 34, 49 kDa respectively) due to a bigger number of protein domains constituting proteins in higher organisms. [48] For instance, yeast proteins are on average 466 amino acids long and 53 kDa in mass. [39]
3309 14828 Ensembl ENSG00000044574 ENSMUSG00000026864 UniProt P11021 P20029 RefSeq (mRNA) NM_005347 NM_001163434 NM_022310 RefSeq (protein) NP_005338 NP_001156906 NP_071705 Location (UCSC) Chr 9: 125.23 – 125.24 Mb Chr 2: 34.66 – 34.67 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Binding immunoglobulin protein (BiPS) also known as 78 kDa glucose-regulated protein (GRP-78) or ...
This type of globulin is found in many different plants such as tomatoes, corn, wheat, and carrots. There was a genome sequence analysis performed on several plants to see if the gene Bg7S was present in each one and it showed that this gene was present in each plant that was tested meaning that this gene is universal in each plant. [11]
The Early 35 kDa protein, or P35 in short, is a baculoviral protein that inhibits apoptosis in the cells infected by the virus. Although baculoviruses infect only invertebrates in nature, ectopic expression of P35 in vertebrate animals and cells also results in inhibition of apoptosis, thus indicating a universal mechanism.