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Epidemics and pandemics with at least 1 million deaths Rank Epidemics/pandemics Disease Death toll Percentage of population lost Years Location 1 1918 Flu: Influenza A/H1N1: 17–100 million 1–5.4% of global population [4] 1918–1920 Worldwide 2 Plague of Justinian: Bubonic plague 15–100 million 25–60% of European population [5] 541–549
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
HIV/AIDS pandemic: Worldwide: 1981–present Human immunodeficiency virus (HIV) ... Note: Only 2 cases in recorded history. Rank Death toll Event Location Date 1. 1,744
The Spanish Flu, the second deadliest pandemic in history after the bubonic plague, along with the aftermath of World War I and ensuing political and social chaos, made 1918 a tough time to be alive.
[1] [25] Some historians believe the first plague pandemic was one of the deadliest pandemics in history, resulting in the deaths of an estimated 15–100 million people during two centuries of recurrence, a death toll equivalent to 25–60% of Europe's population at the time of the first outbreak.
It was the last great pandemic of the 19th century, and is among the deadliest pandemics in history. [2] [3] The pandemic killed about 1 million people out of a world population of about 1.5 billion (0.067% of population). [4] [5] The most reported effects of the pandemic took place from October 1889 to December 1890, with recurrences in March ...
The term pandemic had not been used then, but was used for later epidemics, including the 1918 H1N1 influenza A pandemic—more commonly known as the Spanish flu—which is the deadliest pandemic in history. The most recent pandemics include the HIV/AIDS pandemic, the 2009 swine flu pandemic and the COVID-19 pandemic. Almost all these diseases ...
During the first wave of the pandemic, from April to June 2020, New York and New Jersey were hit particularly hard. Both states saw an excess mortality rate of about 6 per 10,000 people per month.