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The Saccharomyces Genome Database (SGD) is a scientific database of the molecular biology and genetics of the yeast Saccharomyces cerevisiae, which is commonly known as baker's or budding yeast. [1] Further information is located at the Yeastract curated repository.
Saccharomyces cerevisiae was the first eukaryotic organism to have its complete genome sequence determined.. This list of "sequenced" eukaryotic genomes contains all the eukaryotes known to have publicly available complete nuclear and organelle genome sequences that have been sequenced, assembled, annotated and published; draft genomes are not included, nor are organelle-only sequences.
The S. cerevisiae genome is composed of about 12,156,677 base pairs and 6,275 genes, compactly organized on 16 chromosomes. [55] Only about 5,800 of these genes are believed to be functional. It is estimated at least 31% of yeast genes have homologs in the human genome. [57] Yeast genes are classified using gene symbols (such as Sch9) or ...
In genetics, Flp-FRT recombination is a site-directed recombination technology, increasingly used to manipulate an organism's DNA under controlled conditions in vivo.It is analogous to Cre-lox recombination but involves the recombination of sequences between short flippase recognition target (FRT) sites by the recombinase flippase (Flp) derived from the 2 μ plasmid of baker's yeast ...
petite (ρ–) is a mutant first discovered in the yeast Saccharomyces cerevisiae.Due to the defect in the respiratory chain, 'petite' yeast are unable to grow on media containing only non-fermentable carbon sources (such as glycerol or ethanol) and form small colonies when grown in the presence of fermentable carbon sources (such as glucose).
Recombinant DNA molecules are sometimes called chimeric DNA because they can be made of material from two different species like the mythical chimera. rDNA technology uses palindromic sequences and leads to the production of sticky and blunt ends. The DNA sequences used in the construction of recombinant DNA molecules can originate from any ...
Stephen Joseph Elledge Born (1956-08-07) August 7, 1956 (age 68) Paris, Illinois Nationality American Education University of Illinois Urbana-Champaign (BSc) Massachusetts Institute of Technology (PhD) Known for Cell cycle research DNA repair research Spouse Mitzi Kuroda Awards NAS Award in Molecular Biology Breakthrough Prize in Life Sciences Genetics Society of America Medal Dickson Prize ...
The yeast Saccharomyces cerevisiae possesses a minor isoform of large subunit of ribonucleotide-diphosphate reductase under the designation RNR3 or YIL066C on the yeast chromosome IX. [17] It is a paralog of the yeast RNR1, which likely arose from a whole genome duplication event. [18]