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Schamberg's disease, (also known as "progressive pigmentary dermatosis of Schamberg", [1] "purpura pigmentosa progressiva" (PPP), [1] and "Schamberg's purpura" [1]) is a chronic discoloration of the skin found in people of all ages, usually only affecting the feet, legs or thighs or a combination. It may occur as a single event or subsequent ...
Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis. Melanin is a class of pigment responsible for producing color in the body in places such as the eyes, skin, and hair.
This is an accepted version of this page This is the latest accepted revision, reviewed on 11 February 2025. "Skin pigmentation" redirects here. For animal skin pigmentation, see Biological pigment. Extended Coloured family from South Africa showing some spectrum of human skin coloration Human skin color ranges from the darkest brown to the lightest hues. Differences in skin color among ...
In advanced lipodermatosclerosis the proximal leg swells from chronic venous obstruction and the lower leg shrinks from chronic ulceration and fat necrosis resulting in the inverted coke bottle appearance of the lower leg. [7] Lipodermatosclerosis is most commonly diagnosed in middle-aged women. [3]
Acanthosis nigricans is a medical sign characterised by brown-to-black, poorly defined, velvety hyperpigmentation of the skin. [1] It is usually found in body folds, [2] such as the posterior and lateral folds of the neck, the armpits, groin, navel, forehead and other areas.
Photoaging of a woman. Photoaging or photoageing [ 1 ] (also known as "dermatoheliosis" [ 2 ] ) is a term used for the characteristic changes to skin induced by chronic UVA and UVB exposure. [ 3 ] : 29
An intramucosal nevus is a nevus within the mucosa as found in for example the mouth and genital areas. In the mouth, they are found most frequently on the hard palate. They are typically light brown and dome-shaped. [12] Intramucosal nevi account for 64% of all reported case of oral nevi. [13]
Characteristic pigmented melanocytes between bundles of collagen. H&E stain. Spitz nevus: A distinct variant of intradermal nevus, usually in a child. They are raised and reddish (non-pigmented). Characteristic vertically arranged nests of cells ("hanging bananas"). H&E stain. Giant pigmented nevus: Large, pigmented, often hairy congenital nevi.