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Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. [1] Symptoms vary among people and may be mild to severe. [ 1 ]
Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. [1] Symptoms of these diseases can affect many different body systems, including joints , skin , kidneys , blood cells , heart , and lungs .
He also identified discoid lupus erythematosus in Jackson. He diagnosed Jackson with lupus that year, [12] and with vitiligo in 1986. [13] Vitiligo's drastic effects on the body can cause psychological distress.
T he 1.5 million Americans estimated to have the autoimmune disease lupus already have plenty to manage—what with the pain, fatigue, hair loss, and heart problems the condition can cause. So ...
Lupus is typically treated with anti-inflammatory medicines like ibuprofen, hydroxychloroquine for fatigue and skin and joint problems and with steroid tablets, injections and creams for kidney ...
The comparison showed that people with lupus have too much of a particular T cell associated with damage in healthy cells and too little of another T cell associated with repair.
Discoid lupus erythematosus is the most common type of chronic cutaneous lupus (CCLE), an autoimmune skin condition on the lupus erythematosus spectrum of illnesses. [ 1 ] [ 2 ] It presents with red, painful, inflamed and coin-shaped patches of skin with a scaly and crusty appearance, most often on the scalp, cheeks, and ears.
In systemic lupus there are autoantibodies to DNA, which cannot evoke a T cell response, and limited evidence for T cell responses implicates nucleoprotein antigens. In Celiac disease there are autoantibodies to tissue transglutaminase but the T cell response is to the foreign protein gliadin.
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