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  2. Sirolimus - Wikipedia

    en.wikipedia.org/wiki/Sirolimus

    Serious side effects including hypersensitivity and swelling have been observed in renal transplant patients. [22] While sirolimus was considered for treatment of LAM, it received orphan drug designation status because LAM is a rare condition. [22] The safety of LAM treatment by sirolimus in people younger than 18 years old has not been tested.

  3. mTOR inhibitors - Wikipedia

    en.wikipedia.org/wiki/MTOR_inhibitors

    mTOR inhibitors are a class of drugs used to treat several human diseases, including cancer, autoimmune diseases, and neurodegeneration. They function by inhibiting the mammalian target of rapamycin (mTOR) (also known as the mechanistic target of rapamycin), which is a serine/threonine-specific protein kinase that belongs to the family of phosphatidylinositol-3 kinase (PI3K) related kinases ...

  4. Early Results Of Dog Longevity Treatment Show Promise - AOL

    www.aol.com/early-results-dog-longevity...

    One of them, Billy, has become one of the first dozen pets to be injected with a gene therapy treatment intended to extend dog longevity. "I was thrilled to get him into the program," Crommett said.

  5. 7 Alternatives to Chemotherapy for Lymphoma in Dogs - AOL

    www.aol.com/7-alternatives-chemotherapy-lymphoma...

    1. Ketogenic Diet. Cancer cells rely on glucose for energy to grow. The ketogenic diet is a way to provide an alternative energy source to normal cells in the dog's body while starving the cancer ...

  6. Dog Aging Project - Wikipedia

    en.wikipedia.org/wiki/Dog_Aging_Project

    Chemical structure of rapamycin, a pharmaceutical under evaluation for its effects on longevity. The project engages the general public to register their dogs in the studies, and therefore the project is an example of citizen science. [3] As of 2022 nearly 40,000 dogs have been registered with the project. [1]

  7. Why I Started and Stopped Taking the “Anti-Aging” Drug Rapamycin

    www.aol.com/why-started-stopped-taking-anti...

    By 2006, an extensive body of work from several independent studies, including studies from yeast to mammals, all pointed to rapamycin as having an anti-aging effect or at least slowing down the ...

  8. Everolimus - Wikipedia

    en.wikipedia.org/wiki/Everolimus

    Inhibition of mTOR, the molecular target of everolimus, extends the lifespan of model organisms including mice, [37] and mTOR inhibition has been suggested as an anti-aging therapy. Everolimus was used in a clinical trial by Novartis, and short-term treatment was shown to enhance the response to the influenza vaccine in the elderly, possible by ...

  9. Scientists Are Testing a Pill to Make Dogs Stop Aging - AOL

    www.aol.com/lifestyle/scientists-testing-pill...

    This startup is developing an anti-aging pill for dogs that actually works. And if the drug is successful, humans could be next. Scientists Are Testing a Pill to Make Dogs Stop Aging

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