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Mirtazapine is sometimes described as a noradrenergic and specific serotonergic antidepressant (NaSSA), [11] although the actual evidence in support of this label has been regarded as poor. [17] It is a tetracyclic piperazine-azepine. [85] Mirtazapine has antihistamine, α 2-blocker, and antiserotonergic activity.
Chemical structure of the prototypical NaSSA mirtazapine (original brand name Remeron). Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1]
Management of ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) focuses on symptoms management, as no treatments that address the root cause of the illness are available. [1]: 29 Pacing, or regulating one's activities to avoid triggering worse symptoms, is the most common management strategy for post-exertional malaise.
Montel Williams remembers how easy it once was to build a stockpile of opioids when he was on the road. “As celebrities, we can get whatever we want,” Williams, 68, tells Maria Menounos on the ...
For instance, if brain zaps make you feel dizzy, it may help to move slowly and carefully until the feeling passes or have an emergency plan in place in case you get dizzy while exercising, for ...
The reasoning so far is simple: Just as a GLP-1 can make eating food less enjoyable because it modulates your brain’s pleasure and reward center, doctors say that it could impact how you feel ...
Besides mirtazapine, they also block the α 1-adrenergic receptor [citation needed]. Conversely, whereas TCAs have relatively low affinity for the α 2 -adrenergic receptor , mianserin and mirtazapine potently antagonize this receptor, and this action is thought to be involved in their antidepressant effects [ citation needed ] .
Speaking to TODAY.com, Janie Ippolito says she thought the trend was “the funniest thing," so she and her husband, Dave Ippolito, decided to make a video. But the comments section was filled ...