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The heart is a muscular organ situated in the mediastinum.It consists of four chambers, four valves, two main arteries (the coronary arteries), and the conduction system. The left and right sides of the heart have different functions: the right side receives de-oxygenated blood through the superior and inferior venae cavae and pumps blood to the lungs through the pulmonary artery, and the left ...
The heart is a muscular organ found in most animals.This organ pumps blood through the blood vessels. [1] Heart and blood vessels together make the circulatory system. [2] The pumped blood carries oxygen and nutrients to the tissue, while carrying metabolic waste such as carbon dioxide to the lungs. [3]
The heart's cardiac skeleton comprises four dense connective tissue rings that encircle the mitral and tricuspid atrioventricular (AV) canals and extend to the origins of the pulmonary trunk and aorta. This provides crucial support and structure to the heart while also serving to electrically isolate the atria from the ventricles. [1]
The heart did not pump blood around, the heart's motion sucked blood in during diastole and the blood moved by the pulsation of the arteries themselves. Galen believed that the arterial blood was created by venous blood passing from the left ventricle to the right by passing through 'pores' in the interventricular septum, air passed from the ...
The heart and its performance are also commonly measured in terms of dimensions, which in this case means one-dimensional distances, usually measured in millimeters. This is not as informative as volumes but may be much easier to estimate with (e.g., M-Mode echocardiography [ 17 ] or with sonomicrometry , which is mostly used for animal model ...
Mutations in the intercalated disc gene are responsible for various cardiomyopathies that can lead to heart failure. [2] Ruptured intercalated discs, in this case regarded as a visual artifact. Ruptured intercalated discs, when seen on histopathology, have two main causes: Microtome sectioning, thereby being a visual artifact. [4]
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The trabeculae carneae and the papillary muscles make up a significant percentage of the ventricular mass in the heart (12-17% in normal human adult hearts), and are correlated with ventricular end diastolic volume. [5] Trabeculae ratios of capillary-to myocyte differ between the walls of the right and left ventricle.