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  2. Prothrombin time - Wikipedia

    en.wikipedia.org/wiki/Prothrombin_time

    The normal range for a healthy person not using warfarin is 0.8–1.2, and for people on warfarin therapy an INR of 2.0–3.0 is usually targeted, although the target INR may be higher in particular situations, such as for those with a mechanical heart valve. If the INR is outside the target range, a high INR indicates a higher risk of bleeding ...

  3. Alcohol and health - Wikipedia

    en.wikipedia.org/wiki/Alcohol_and_health

    Enzymes. Women have lower levels of two enzymes—alcohol dehydrogenase and aldehyde dehydrogenase—that metabolize (break down) alcohol in the stomach and liver. As a result, women absorb more alcohol into their bloodstreams than men. Hormones. Changes in hormone levels during the menstrual cycle may also affect how a woman metabolizes alcohol.

  4. Alcohol and cardiovascular disease - Wikipedia

    en.wikipedia.org/wiki/Alcohol_and_cardiovascular...

    III. For people who consumed 6 or more drinks per day, reduction rate on blood pressure was the strongest when they reduced alcohol consumption close to abstinence. IV. The effect of alcohol reduction on blood pressure is still unclear for women and hypertensive patients who consume less than three drinks per day due to limited clinical trials.

  5. Alcoholic cardiomyopathy - Wikipedia

    en.wikipedia.org/wiki/Alcoholic_cardiomyopathy

    Interestingly, in patients that are defined as "heavy drinkers" (defined as consuming >30g of alcohol/day) decreased alcohol consumption to moderate levels has been shown to be an effective treatment; in fact [12] A retrospective cohort study analyzed data collected from over 3.8 million patients, and categorized patients as either abstinent ...

  6. Warfarin - Wikipedia

    en.wikipedia.org/wiki/Warfarin

    Vitamin K1-warfarin interaction effect: When warfarin levels are high, people have more risk of bleeding. Conversely, lower levels of warfarin lead to increased risk of blood clots. A narrow range exists where the benefits of warfarin are greater than the risks, its therapeutic window. Certain drugs, herbal medicines, and foods can interact ...

  7. Liver function tests - Wikipedia

    en.wikipedia.org/wiki/Liver_function_tests

    In patients with liver disease, international normalized ratio (INR) can be used as a marker of liver synthetic function as it includes factor VII, which has the shortest half life (2–6 hours) of all coagulation factors measured in INR. An elevated INR in patients with liver disease, however, does not necessarily mean the patient has a ...

  8. Alcoholic hepatitis - Wikipedia

    en.wikipedia.org/wiki/Alcoholic_hepatitis

    Alcoholic hepatitis is distinct from cirrhosis caused by long-term alcohol consumption. Alcoholic hepatitis can occur in patients with chronic alcoholic liver disease and alcoholic cirrhosis. Alcoholic hepatitis by itself does not lead to cirrhosis, but cirrhosis is more common in patients with long term alcohol consumption. [6]

  9. Holiday heart syndrome - Wikipedia

    en.wikipedia.org/wiki/Holiday_heart_syndrome

    Holiday heart syndrome, also known as alcohol-induced atrial arrhythmias, is a syndrome defined by an irregular heartbeat and palpitations [1] associated with high levels of ethanol consumption. [2] Holiday heart syndrome was discovered in 1978 when Philip Ettinger discovered the connection between arrhythmia and alcohol consumption. [ 3 ]

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