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Mirtazapine, sold under the brand name Remeron among others, is an atypical tetracyclic antidepressant, and as such is used primarily to treat depression. [11] [12] Its effects may take up to four weeks but can also manifest as early as one to two weeks.
Meclizine, sold under the brand name Bonine, among others, is an antihistamine used to treat motion sickness and dizziness . [3] It is taken by mouth. [3] Effects generally begin in an hour and last for up to a day. [3] Common side effects include sleepiness and dry mouth. [3] Serious side effects may include allergic reactions. [3]
Clobazam is sometimes used for refractory epilepsies. However, long-term prophylactic treatment of epilepsy may have considerable drawbacks, most importantly decreased antiepileptic effects due to drug tolerance which may render long-term therapy less effective. [10]
Protriptyline is available as 5 mg and 10 mg tablets. [5] Doses range from 15 to 40 mg per day and can be taken in one daily dose or divided into up to four doses daily. [5] Some people with severe depression may require up to 60 mg per day. [5]
Dosages of 50 mg to 75 mg daily are usually satisfactory as maintenance therapy for elderly patients who do not tolerate higher amounts. [ 21 ] [ 22 ] In any case, 225 m.g./d. is the absolute-maximum highest recommended dose for this drug, as any more can predispose more significantly to seizures. 150 m.g. is the average optimal daily dose for ...
Hydroxyzine works by blocking the effects of histamine. [9] It is a first-generation antihistamine in the piperazine family of chemicals. [8] [4] Common side effects include sleepiness, headache, and dry mouth. [8] [9] Serious side effects may include QT prolongation. [9] It is unclear if use during pregnancy or breastfeeding is safe. [8]
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