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Osteocytes, the most common cell type within mature cortical bone, actively participate in the growth and maintenance of TCVs through the transfer of mitochondria to endothelial cells. Scanning electron microscopy images have revealed that osteocytes possess numerous dendritic processes with expanded, endfoot-like structures. These endfeet ...
Intercellular transfer of mitochondria in culture has been documented from MSCs and endothelial cells to breast cancer cell lines, ovarian cancer cell lines or to osteosarcoma cell line. [11] Mitochondrial transfer can occur also between cancer cells such as mesothelioma [12] and laryngeal carcinoma cells. [13]
Depiction of mitochondrial membranes. [1] Mitochondrial membrane transport proteins, also known as mitochondrial carrier proteins, are proteins which exist in the membranes of mitochondria. They serve to transport [2] molecules and other factors, such as ions, into or out of the organelles. Mitochondria contain both an inner and outer membrane ...
Endothelial microparticles are small vesicles that are released from endothelial cells and can be found circulating in the blood. [ 13 ] The microparticle consists of a plasma membrane surrounding a small amount of cytosol .
The grey area is the inner mitochondrial membrane. Q represents the ubiquinone form of CoQ, and QH 2 represents the ubiquinol ( dihydroxyquinone ) form. The Q cycle (named for quinol ) describes a series of sequential oxidation and reduction of the lipophilic electron carrier Coenzyme Q (CoQ) between the ubiquinol and ubiquinone forms.
Many MC proteins preferentially catalyze the exchange of one solute for another ().A variety of these substrate carrier proteins, which are involved in energy transfer, have been found in the inner membranes of mitochondria and other eukaryotic organelles such as the peroxisome and facilitate the transport of inorganic ions, nucleotides, amino acids, keto acids and cofactors across the membrane.
Endothelium lines the inner wall of vessels, shown here. Microscopic view showing endothelium (at top) inside the heart. The endothelium forms an interface between circulating blood or lymph in the lumen and the rest of the vessel wall. This forms a barrier between vessels and tissues and control the flow of substances and fluid into and out of ...
Currently, this "inside-out" hypothesis (which states that the alphaproteobacteria, the ancestral mitochondria, were engulfed by the blebs of an asgardarchaeon, and later the blebs fused leaving infoldings which would eventually become the endomembrane system) is favored more than the outside-in one (which suggested that the endomembrane system ...