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While the FDA approved the use of generic levothyroxine for brand-name levothyroxine in 2004, the decision was met with disagreement by several medical associations. [14] The American Association of Clinical Endocrinologists (AACE), the Endocrine Society , and the American Thyroid Association did not agree with the FDA that brand-name and ...
Tetracycline was patented in 1953 [6] and was approved for prescription use in 1954. [7] [8] It is on the World Health Organization's List of Essential Medicines. [9] Tetracycline is available as a generic medication. [3] Tetracycline was originally made from bacteria of the genus Streptomyces. [3]
Drug nomenclature is the systematic naming of drugs, especially pharmaceutical drugs.In the majority of circumstances, drugs have 3 types of names: chemical names, the most important of which is the IUPAC name; generic or nonproprietary names, the most important of which are international nonproprietary names (INNs); and trade names, which are brand names. [1]
Levothyroxine, a drug used to treat hypothyroidism, can lead to reduced bone mass and density in older adults with normal thyroid levels, a small cohort study has shown.
For patients taking levothyroxine, TSH may be boosted by discontinuing levothyroxine for 3–6 weeks. [5] This long period of hormone withdrawal is required because of levothyroxine's relatively long biological half-life, and may result in symptoms of hypothyroidism in the patient. The shorter half-life of liothyronine permits a withdrawal ...
Doxycycline, a tetracyclic antibiotic. Mirtazapine, a tetracyclic antidepressant. Tetracyclics are cyclic chemical compounds that contain four fused rings of atoms, for example, Tröger's base.
The Federal Trade Commission found that the cross-license, combined with the fact that Pfizer had withheld information that it knew or should have known was relevant to the patentability of tetracycline, constituted an attempt by Pfizer and American Cyanamid to share in an unlawful monopoly. [3] Ultimately, the government lost. [4]
Tetracyclines are generally used in the treatment of infections of the urinary tract, respiratory tract, and the intestines and are also used in the treatment of chlamydia, especially in patients allergic to β-lactams and macrolides; however, their use for these indications is less popular than it once was due to widespread development of resistance in the causative organisms.