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Recurrent ulceration and fat necrosis is associated with lipodermatosclerosis. In advanced lipodermatosclerosis the proximal leg swells from chronic venous obstruction and the lower leg shrinks from chronic ulceration and fat necrosis resulting in the inverted coke bottle appearance of the lower leg.
Pancreatic panniculitis (also known as enzymatic panniculitis, Pancreatic fat necrosis, [10] and subcutaneous fat necrosis) is a panniculitis most commonly associated with pancreatic carcinoma, and more rarely with anatomic pancreatic abnormalities, pseudocysts, or drug-induced pancreatitis. [2]: 493
Fat necrosis is necrosis affecting fat tissue (adipose tissue). [1] The term is well-established in medical terminology despite not denoting a specific pattern of necrosis. [ 2 ] Fat necrosis may result from various injuries to adipose tissue, including: physical trauma, enzymatic digestion of adipocytes by lipases , [ 3 ] radiation therapy ...
Axial fat suppressed T2 weighted MRI image showing hyperintense signal and enlargement of the left thigh adductor muscle group in diabetic myonecrosis. Axial fat suppressed post gadolinium contrast enhancement MRI image showing absent enhancement in the left thigh adductor muscles centrally indicating necrosis in diabetic myonecrosis.
Mobile encapsulated fat necrosis (MEFN) is a rare medical condition featuring the formation of a fibrotic capsule around a small, necrotic mass of fatty tissue. It is asymptomatic and benign but may be mistaken for other neoplasms due to its typical presentation as a firm nodule beneath the skin that can be moved around within the tissue.
Breast and trunk lymphedema can also occur but go unrecognised as there is swelling in the area after surgery, and its symptoms (peau d'orange and an inverted nipple) can be confused with post surgery fat necrosis. [16] Between 38 and 89% of breast cancer patients have lymphedema due to axillary lymph node dissection or radiation.
Necrobiosis lipoidica is a rare, chronic skin condition predominantly associated with diabetes mellitus (known as necrobiosis lipoidica diabeticorum or NLD). [1] It can also occur in individuals with rheumatoid arthritis or without any underlying conditions (). [2]
Erythema nodosum (EN) is an inflammatory condition characterized by inflammation of subcutaneous fat tissue, resulting in painful red/blue lumps or nodules that are usually seen symmetrically on both shins, on the thighs, arms, and elsewhere. [1] It can be caused by a variety of conditions but 20 to 50% of cases are idiopathic.