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Measurements of the total wall thickness of blood vessels can also be done using other imaging modalities. Carotid IMT is used to detect the presence of atherosclerosis in humans and, more contentiously, to track the regression, arrest or progression of atherosclerosis. [1] Ultrasound measurements of carotid IMT were first proposed and ...
Since the wall thickness, radius and incremental elastic modulus vary from blood vessel to blood vessel, PWV will also vary between vessels. [11] Most measurements of PWV represent an average velocity over a path length consisting of several vessels (e.g. from the carotid to the femoral artery). [14]
Regardless of site, blood pressure is related to the wall tension of the vessel according to the Young–Laplace equation (assuming that the thickness of the vessel wall is very small as compared to the diameter of the lumen): = where P is the blood pressure; t is the wall thickness
Blood viscosity is the thickness of the blood and its resistance to flow as a result of the different components of the blood. Blood is 92% water by weight and the rest of blood is composed of protein, nutrients, electrolytes, wastes, and dissolved gases.
The Moens–Korteweg equation states that PWV is proportional to the square root of the incremental elastic modulus, (E inc), of the vessel wall given constant ratio of wall thickness, h, to vessel radius, r, and blood density, ρ, assuming that the artery wall is isotropic and experiences isovolumetric change with pulse pressure. [5]
Blood viscosity is a measure of the resistance of blood to flow. It can also be described as the thickness and stickiness of blood. This biophysical property makes it a critical determinant of friction against the vessel walls, the rate of venous return, the work required for the heart to pump blood, and how much oxygen is transported to tissues and organs.
Differences in vascular permeability between normal tissue and a tumor. Vascular permeability, often in the form of capillary permeability or microvascular permeability, characterizes the capacity of a blood vessel wall to allow for the flow of small molecules (drugs, nutrients, water, ions) or even whole cells (lymphocytes on their way to the site of inflammation) in and out of the vessel.
The structure of the tunica intima depends on the blood vessel type. [3] Elastic arteries – A single layer of endothelial and a supporting layer of elastin-rich collagen. The layer also contains fibroblasts, immune cells and smooth muscle cells. [1] Muscular arteries – Endothelial cells Arterioles – A single layer of endothelial cells