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Sucralfate is a locally acting substance that in an acidic environment (pH < 4) reacts with hydrochloric acid in the stomach to form a cross-linking, viscous, paste-like material capable of acting as an acid buffer for as long as 6 to 8 hours after a single dose. [29]
Carafate; Sucralfate; Hydroxyaluminium, Al(OH), also known as monobasic aluminium or basic aluminium, is divalent, and known in these compounds: Hydroxyaluminium diacetate, HOAl(CH 3 CO 2) 2, also known as aluminium diacetate, basic aluminium diacetate, basic aluminium acetate, monobasic aluminium acetate; Aluminium, Al, is trivalent.
From or to a drug trade name: This is a redirect from (or to) the trade name of a drug to (or from) the international nonproprietary name (INN).
The H 2 receptor antagonists are a class of drugs used to block the action of histamine on parietal cells in the stomach, decreasing the production of acid by these cells. H 2 antagonists are used in the treatment of dyspepsia, although they have been surpassed in popularity by the more effective [1] proton pump inhibitors.
The GI cocktail is a mixture of a viscous anesthetic, an antacid, and an anticholinergic. [1] [2] Common viscous anesthetics use are viscous lidocaine or xylocaine.Common antacids used are magnesium hydroxide, aluminum hydroxide, or simethicone (more commonly known as Mylanta or Maalox). [3]
Famotidine, sold under the brand name Pepcid among others, is a histamine H 2 receptor antagonist medication that decreases stomach acid production. [4] It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. [4]
Sucralfate has similar effectiveness to H 2 receptor blockers; however, sucralfate needs to be taken multiple times a day, thus limiting its use. [9] Baclofen, an agonist of the GABA B receptor, while effective, has similar issues of needing frequent dosing in addition to greater adverse effects compared to other medications. [9]
I just noticed that sentence and thought the same. Since sucralfate has a protective effect (binds to the ulcer), that would seem to be a reason for using it for gastric ulcers. Maybe need to check the FDA docs on it. As far as other uses, it's common for meds to be used for non-FDA approved uses, where it is thought they are effective.
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109 S High St #100, Columbus, OH · Directions · (614) 224-4261
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