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The Allen Mouse Brain Atlas is a comprehensive genome-wide map of the adult mouse brain that reveals where each gene is expressed. [3] The mouse brain atlas was the original project of the Allen Brain Atlas and was finished in 2006. The purpose of the atlas is to aid in the development of neuroscience research.
On November 14, 2008, the Allen Institute for Brain Science announced the launch of the Allen Developing Mouse Brain Atlas, providing a highly detailed map of gene activity in the mouse brain at several time points across development, [12] including four embryonic ages, three postnatal, and aging time points. [13]
The Blue Brain Project was able to model these networks using algebraic topology. [13] In 2018, Blue Brain Project released its first digital 3D brain cell atlas [14] which, according to ScienceDaily, is like "going from hand-drawn maps to Google Earth", providing information about major cell types, numbers, and positions in 737 regions of the ...
The house mouse (Mus musculus) has a gestation period of 19 to 21 days. Key events in mouse brain development occur both before and after birth, beginning with peak neurogenesis of the cranial motor nuclei 9 days after conception, up to eye opening which occurs after birth and about 30 days after conception.
Mouse brain, lateral view. The mouse brain refers to the brain of Mus musculus. Various brain atlases exist. For reasons of reproducibility, genetically characterized, stable strains like C57BL/6 were chosen to produce high-resolution images and databases. [1] Well known online resources include: Allen Brain Atlas [2] Mouse Brain Library [3]
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Other bone morphogenetic proteins are also known to impact corticogenesis in the mouse. Bmp2, 4, 5, and 6 are expressed during the process and can compensate for one another. For example, if Bmp-4 was absent from corticogenesis, very little would change in the cortex phenotype, due to the other Bmps helping accomplish the tasks of Bmp-4.
Besides the human brain, [4] brain atlases exist for the brains of the mouse, [5] rhesus macaques, [6] Drosophila, [7] pig [8] and others. Notable examples include the Allen Brain Atlas , BrainMaps , BigBrain , Infant Brain Atlas , [ 9 ] and the work of the International Consortium for Brain Mapping (ICBM).