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Unlike the latter two procedures, the XEN Gel Stent is performed through an internal approach and avoids directly incising and disrupting the conjunctiva itself. [34] [35] The 6-millimeter stent is placed through the trabecular meshwork, with one end of the stent sitting directly underneath the conjunctiva, past the outer wall of the sclera ...
Examples of Trabeculectomy-modifying devices are Ex-PRESS, Gelfilm, XEN Gel stent, antifibrotic materials (e.g Ologen), ePTFE (expanded polytetrafluoroethylene) membrane and PreserFlo MicroShunt. Comparing each of these devices for effectiveness and safety is required. [10]
The LEI is acknowledged as a core academic centre involved in clinical trials of new pharmaceutical therapies and surgical procedures before government approval. For example, the Xen Gel Stent, an implantable transcleral microsurgical device developed at the LEI, was approved for use in the US by the FDA in 2016. [13]
The first glaucoma drainage implant was developed in 1966. [2] Following on the success of the Molteno implant, several varieties of device have been developed from the original, the Baerveldt tube shunt, or the valved implants, such as the Ahmed glaucoma valve implant and the later generation pressure ridge Molteno implants.
Ab interno implants, such as the Xen Gel Stent, are transscleral implants by an ab interno procedure to channel aqueous humor into the non-dissected Tenon's space, creating a subconjunctival drainage area similar to a bleb.
A stent graft or covered stent is type of vascular stent with a fabric coating that creates a contained tube but is expandable like a bare metal stent. Covered stents are used in endovascular surgical procedures such as endovascular aneurysm repair. Stent grafts are also used to treat stenoses in vascular grafts and fistulas used for hemodialysis.
Like metal stents, placement of a bioresorbable stent will restore blood flow and support the vessel through the healing process. However, in the case of a bioresorbable stent, the stent will gradually resorb and be benignly cleared from the body, enabling a natural reconstruction of the arterial wall and restoration of vascular function. [6]
A bare-metal stent is a stent made of thin, uncoated (bare) metal wire that has been formed into a mesh-like tube. The first stents licensed for use in cardiac arteries were bare metal – often 316L stainless steel. More recent "second generation" bare-metal stents have been made of cobalt chromium alloy. [1]