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Demineralized freeze dried bone allograft, referred to as DFDBA, is a bone graft material known for its de novo bone formation properties. [1] It is used extensively in bone grafting of alveolar bone in oral and periodontal surgery.
Osteopromotion involves the enhancement of osteoinduction without the possession of osteoinductive properties. For example, enamel matrix derivative has been shown to enhance the osteoinductive effect of demineralized freeze dried bone allograft (DFDBA), but will not stimulate new bone growth alone. [4]
In contrast, osteopromotive substances will not contribute to de novo bone growth but serve to enhance the osteoinductivity of osteoinductive materials. An example of this is enamel matrix derivative, which serves to enhance the osteoinductive nature of demineralized freeze dried bone allograft (DFDBA). [1]
Demineralized freeze dried bone allograft (DFDBA) has been histologically proven to be the material of choice for regeneration. Platelet-rich fibrin has shown significant results comparable to DFDBA for periodontal regeneration. [ 12 ]
The most common source of the bone graft is from the iliac crest, [6] harvested at the time of the cleft closure. Other sources such as the chin, and posterior iliac crest, or skull can also be used. Artificial grafts such as demineralized bone, recombinent bone morphogenic protein or a mix of harvested bone and artificial grafts have also been ...
Allograft bone is a logical alternative to autograft. However, it must be rigorously processed and terminally sterilized prior to implantation to remove the risk of disease transmission or an immunological response. This processing removes the osteogenic and osteoinductive properties of the graft, leaving only an osteoconductive scaffold. These ...
Socket preservation or alveolar ridge preservation is a procedure to reduce bone loss after tooth extraction. [1] [2] After tooth extraction, the jaw bone has a natural tendency to become narrow, and lose its original shape because the bone quickly resorbs, resulting in 30–60% loss in bone volume in the first six months. [3]
Severe bone and tissue loss can make it difficult for the proceeding with alloplasty as procedural plans about regenerating bone through alloplastic implants become more complex. [ 13 ] Mock up of artificial shoulder implant that remained in a patient for two years, until removed due to infection.