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Malassezia is a genus of fungi (specifically, a yeast). Some species of Malassezia are found on the skin of animals, including humans. Because malassezia requires fat to grow, [3] it is most common in areas with many sebaceous glands—on the scalp, [4] face, and upper part of the body.
Malassezia furfur (formerly known as Pityrosporum ovale) is a species of yeast (a type of fungus) that is naturally found on the skin surfaces of humans and some other mammals. It is associated with a variety of dermatological conditions caused by fungal infections , notably seborrhoeic dermatitis and tinea versicolor .
Malassezia pachydermatis is a bottle-shaped, [2] non-lipid dependent lipophilic yeast in the genus Malassezia. [5] Colonies are cream or yellowish in colour, smooth to wrinkled and convex with a margin possessing a slightly lobed appearance. [5] [8] Cells are ovoidal in shape and range in size from 3.0–6.5 x 2.5 μm. [5]
Climbazole is a topical antifungal agent commonly used in the treatment of human fungal skin infections such as dandruff, seborrhoeic dermatitis and eczema. [2] Climbazole has shown a high in vitro and in vivo efficacy against Malassezia spp. that appear to play an important role in the pathogenesis of dandruff. [2]
It is considered to be part of the skin's normal human microbiota [2] [6] and begins to colonize the skin of humans shortly after birth. [7] Malassezia sympodialis, often has a symbiotic or commensal relationship with its host, but it can act as a pathogen causing a number of different skin diseases, [8] such as atopic dermatitis. [8] [9]
Seborrheic dermatitis is a chronic condition that typically requires ongoing treatment — so ketoconazole isn’t a one-and-done treatment. Long-term use is often necessary. Long-term use is ...
Species of Malassezia implicated in Seborrhoeic dermatitis include M. furfur (formerly Pityrosporum ovale), M. globosa, M. restricta, M. sympodialis, and M. slooffiae. [ 3 ] Malassezia appears to be the significant factor in seborrhoeic dermatitis but it is thought that other factors are necessary for the presence of Malassezia to result in the ...
This includes people with illnesses such as HIV/AIDS, and people taking medicines such as steroids or cancer treatments. [14] People with diabetes also tend to develop fungal infections. [19] Very young and very old people, also, are groups at risk. [20] Individuals being treated with antibiotics are at higher risk of fungal infections. [21]