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  2. Eosinophilia–myalgia syndrome - Wikipedia

    en.wikipedia.org/wiki/Eosinophilia–myalgia...

    Eosinophilia–myalgia syndrome is a rare, sometimes fatal neurological condition linked to the ingestion of the dietary supplement L-tryptophan. [1] [2] The risk of developing EMS increases with larger doses of tryptophan and increasing age. [3]

  3. Tryptophan - Wikipedia

    en.wikipedia.org/wiki/Tryptophan

    Tryptophan contains an α-amino group, an α-carboxylic acid group, and a side chain indole, making it a polar molecule with a non-polar aromatic beta carbon substituent. Tryptophan is also a precursor to the neurotransmitter serotonin, the hormone melatonin, and vitamin B 3 (niacin). [4] It is encoded by the codon UGG.

  4. N,N-Dimethyltryptamine - Wikipedia

    en.wikipedia.org/wiki/N,N-Dimethyltryptamine

    In plants, the parent amino acid L-tryptophan is produced endogenously where in animals L-tryptophan is an essential amino acid coming from diet. No matter the source of L-tryptophan, the biosynthesis begins with its decarboxylation by an aromatic amino acid decarboxylase (AADC) enzyme (step 1). The resulting decarboxylated tryptophan analog is ...

  5. Essential amino acid - Wikipedia

    en.wikipedia.org/wiki/Essential_amino_acid

    Through manipulation of rodent diets, Rose was able to show that ten amino acids are essential for rats: lysine, tryptophan, histidine, phenylalanine, leucine, isoleucine, methionine, valine, and arginine, in addition to threonine. Rose's later work showed that eight amino acids are essential for adult human beings, with histidine also being ...

  6. L-Tryptophan - Wikipedia

    en.wikipedia.org/?title=L-Tryptophan&redirect=no

    This page was last edited on 25 July 2008, at 18:30 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may ...

  7. α-Methyltryptophan - Wikipedia

    en.wikipedia.org/wiki/Α-Methyltryptophan

    [3] [4] [5] The preceding limitations of tryptophan make its use in PET imaging in humans impossible, whereas αMTP is a viable agent for such purposes. [ 5 ] αMTP is first converted by tryptophan hydroxylase into α-methyl-5-hydroxytryptophan (αM-5-HTP or α-methyl-5-HTP), the α-methylated analogue of 5-hydroxytryptophan (5-HTP), prior to ...

  8. Tryptophan 2,3-dioxygenase - Wikipedia

    en.wikipedia.org/wiki/Tryptophan_2,3-dioxygenase

    56720 Ensembl ENSG00000262635 ENSG00000151790 ENSMUSG00000028011 UniProt P48775 P48776 RefSeq (mRNA) NM_005651 NM_019911 RefSeq (protein) NP_005642 NP_064295 Location (UCSC) Chr 4: 155.85 – 155.92 Mb Chr 3: 81.86 – 81.88 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse In enzymology, tryptophan 2,3-dioxygenase (EC 1.13.11.11) is a heme enzyme that catalyzes the oxidation of L ...

  9. 5-Hydroxytryptophan - Wikipedia

    en.wikipedia.org/wiki/5-Hydroxytryptophan

    5-HTP is produced from the amino acid tryptophan through the action of the enzyme tryptophan hydroxylase. Tryptophan hydroxylase is one of the biopterin-dependent aromatic amino acid hydroxylases. Production of 5-HTP is the rate-limiting step in 5-HT (serotonin) synthesis. 5-HTP is normally rapidly converted to 5-HT by amino acid decarboxylase. [1]

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