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Inventing the AIDS Virus is a 1996 book by molecular biologist Peter Duesberg, in which the author argues that HIV does not cause AIDS.Duesberg contends that HIV is a harmless passenger virus and that AIDS is caused by unrelated factors such as drug abuse, antiretroviral medication, chronic malnutrition, poor sanitation, and hemophilia.
The activation and proliferation of T cells that results from immune activation provides fresh targets for HIV infection. However, direct killing by HIV alone cannot account for the observed depletion of CD4 + T cells since only 0.01–0.10% of CD4 + T cells in the blood are infected. [citation needed]
In 1985, HIV was identified as the causative agent of acquired immune deficiency syndrome (AIDS) and its complete genome was immediately available. This knowledge paved the way for the development of selective inhibitors. [6] HIV-2 carries a slightly lower risk of transmission than HIV-1 and infection tends to progress more slowly to AIDS. [7]
HIV is a retrovirus that primarily infects components of the human immune system such as CD4 + T cells, macrophages and dendritic cells. It directly and indirectly destroys CD4 + T cells. [88] HIV is a member of the genus Lentivirus, [89] part of the family Retroviridae. [90] Lentiviruses share many morphological and biological characteristics.
Two types of HIV have been characterized: HIV-1 and HIV-2. HIV-1 is the virus that was initially discovered and termed both lymphadenopathy associated virus (LAV) and human T-lymphotropic virus 3 (HTLV-III). HIV-1 is more virulent and more infective than HIV-2, [20] and is the cause of the majority of HIV infections globally. The lower ...
Duesberg's claim that recreational drug use, rather than HIV, was the cause of AIDS has been specifically examined and found to be false. Cohort studies have found that only HIV-positive drug users develop opportunistic infections; HIV-negative drug users do not develop such infections, indicating that HIV rather than drug use is the cause of AIDS.
The campaign seeks to spread the scientific evidence that undetectable means untransmittable. Since the beginning of the epidemic, perceptions and management of HIV infection have gone through many stages; from assuming the infectiousness, then discovering the routes of transmission (blood, sexual fluids, and breastfeeding), to prevention methods (education, condoms, PrEP, and PEP) and various ...
He is featured in And the Band Played On, a non-fiction book by San Francisco Chronicle journalist Randy Shilts, which chronicles the discovery and spread of HIV/AIDS. Curran was a pioneer in the field in that he was one of the first scientists to recognize the infectious nature of HIV/AIDS, and he is recognized for fighting the stigmatization ...