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In 2023, 630,000 people died from HIV-related causes, an estimated 1.3 million people acquired HIV and about 39.9 million people worldwide living with HIV, 65% of whom are in the World Health Organization (WHO) African Region. [5] [7] HIV/AIDS is considered a pandemic—a disease outbreak which is present over a large area and is actively ...
Continuous HIV replication results in a state of generalized immune activation persisting throughout the chronic phase. [6] Immune activation, which is reflected by the increased activation state of immune cells and release of proinflammatory cytokines , results from the activity of several HIV gene products and the immune response to ongoing ...
HIV-1 is more virulent and more infective than HIV-2, [20] and is the cause of the majority of HIV infections globally. The lower infectivity of HIV-2, compared to HIV-1, implies that fewer of those exposed to HIV-2 will be infected per exposure. Due to its relatively poor capacity for transmission, HIV-2 is largely confined to West Africa. [21]
Lentivirus is a genus of retroviruses that cause chronic and deadly diseases characterized by long incubation periods, in humans and other mammalian species. [2] The genus includes the human immunodeficiency virus (HIV), which causes AIDS.
HIV-1 is the most common and most pathogenic strain of the virus. As of 2022, approximately 1.3 million such infections occur annually. [4] [5] Scientists divide HIV-1 into a major group (group M) and two or more minor groups, namely groups N, O and possibly a group P.
A Pennsylvania woman faces indecent assault charges after allegedly attempting to ply two tween boys with alcohol and sexually assault one of them after they shoveled snow from her driveway.
The French doctor Charles Anglada (1809–1878) wrote a book in 1869 on extinct and new diseases. [16] He did not distinguish infectious diseases from others (he uses the terms reactive and affective diseases, to mean diseases with an external or internal cause, more or less meaning diseases with or without an observable external cause).
The Big Ten and Southeastern Conference both have arguments to be considered the top league in women's basketball. Each has seven teams ranked in The Associated Press Top 25 women's basketball ...