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[1] [9] People with latent TB do not spread the disease. [1] Active infection occurs more often in people with HIV/AIDS and in those who smoke. [1] Diagnosis of active TB is based on chest X-rays, as well as microscopic examination and culture of bodily fluids. [10] Diagnosis of latent TB relies on the tuberculin skin test (TST) or blood tests ...
In fact, "it isn't easy to catch TB. You need consistent exposure to the contagious person for a long time. For that reason, you're more likely to catch TB from a relative than a stranger." [7] If a person had latent tuberculosis, they do not have active/contagious tuberculosis. Once exposed, people very often have latent tuberculosis.
In addition, between 1851 and 1910, around four million died from TB in England and Wales – more than one third of those aged 15 to 34 and half of those aged 20 to 24 died from TB. [62] By the late 19th century, 70–90% of the urban populations of Europe and North America were infected with the Mycobacterium tuberculosis , and about 80% of ...
Resistant strains of M. tuberculosis have developed resistance to more than one TB drug, due to mutations in their genes. In addition, pre-existing first-line TB drugs such as rifampicin and streptomycin have decreased efficiency in clearing intracellular M. tuberculosis due to their inability to effectively penetrate the macrophage niche. [31]
Since this one’s a blood test, you don’t need to show up again to have the test read like you do with the PPD. Also, the IGRA is more specific to TB rather than other types of mycobacterial infections and is unlikely to be positive as a result of having BCG vaccine in the past, a vaccine that protects against TB.
Alerting the general public about exposures or outbreaks (IE: COVID-19, Measles, TB, etc.) Offering diagnosis, counseling and treatment to already infected individuals; If the infection is treatable, helping prevent reinfection of the originally infected patient; Learning about the epidemiology of a disease in a particular population
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Elimination of tuberculosis is the effort to reduce the number of tuberculosis (TB) cases to less than one per 1 million population, contrasted with the effort to completely eradicate infection in humans worldwide. [1]