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PCB-containing solid material was widely used as fill, including oxbows of the Housatonic River. Fish and waterfowl which live in and around the river contain significant levels of PCBs and are not safe to eat. [144] EPA designated the Pittsfield plant and several miles of the river as a Superfund site in 1997, and ordered GE to remediate the ...
Olestra was approved by the Food and Drug Administration for use as a food additive in 1996 and was initially used in potato chips under the WOW brand by Frito Lay.In 1998, the first year olestra products were marketed nationally after the FDA's Food Advisory Committee confirmed a judgment it made two years earlier, sales were over $400 million.
Bioremediation of PCBs is the use of microorganisms to degrade PCBs from contaminated sites, relying on multiple microorganisms' co-metabolism. Anaerobic microorganisms dechlorinate PCBs first, and other microorganisms that are capable of doing BH pathway can break down the dechlorinated PCBs to usable intermediates like acyl-CoA or carbon ...
PCB-compounds, always containing low concentrations of dioxin-like PCBs and PCDFs, were synthesized for various technical purposes (see Polychlorinated biphenyls). They have entered the environment through accidents such as fires or leaks from transformers or heat exchangers, or from PCB-containing products in landfills or during incineration.
The inclusion of PCBs as a PBT may be attributed to their low water solubility, high stability, and semi-volatility facilitating their long range transport and accumulation in organisms. [5] The persistence of these compounds is due to the high resistance to oxidation, reduction, addition, elimination and electrophilic substitution. [ 6 ]
Exposure to the coplanar stereoisomer 3,3',4,4',5,5'-hexabromobiphenyl (but not the non-coplanar stereoisomer) in genetically susceptible mice is known to cause immunotoxicity and disorders related to the central nervous system, and even at doses as low as 2.5 mg/kg, excess neonatal fatalities are observed (LD 50 is from 5–10 mg/kg). [1]
Red dye No. 3 was banned, among other popular food additives, in California. What to know about related health risks, and what products you may want to avoid.
PCBs are toxic to fish at high doses, and associated with spawning failure at low doses. Human exposure occurs through food, and is associated with reproductive failure and immune suppression. Immediate effects of PCB exposure include pigmentation of nails and mucous membranes and swelling of the eyelids, along with fatigue, nausea, and vomiting.
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