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Studies comparing lidocaine and articaine found that articaine is more effective than lidocaine in anaesthetising the posterior first molar region. [12] Articaine has been found to be 3.81 times more likely than lidocaine to produce successful anaesthesia when used for infiltration injections.
This is due to the use of different constituents. Local Anaesthetics which contain adrenaline such as Lidocaine (using 1:80,000 of adrenaline) or Articaine (using 1:100,000 of adrenaline) have a direct effect on the cardiac output by increasing the rate and contraction of the heart itself.
Many local anesthetics fall into two general chemical classes, amino esters (top) and amino amides (bottom). A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, [1] providing local anesthesia, as opposed to a general anesthetic, which eliminates all sensation in the entire body and causes ...
With an estimated 52.5 million adults in the U.S. affected by arthritis alone and up to 24% of adults experiencing muscle pain during their lifetime, effective topical pain relievers can be life ...
Amide-linked local anesthetic agents, such as lidocaine and bupivacaine, can become "trapped" in their ionized forms on the fetal side of the placenta, so their net transfer across the placenta is increased. An ester-linked local anesthetic agent, such as 2-chloroprocaine, is rapidly metabolized, and placental transfer is limited.
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Lidocaine is an antiarrhythmic medication of the class Ib type. [7] This means it works by blocking sodium channels thus decreasing the rate of contractions of the heart. [10] [7] When injected near nerves, the nerves cannot conduct signals to or from the brain. [8] Lidocaine was discovered in 1946 and went on sale in 1948. [11]
Side effects from using ear drops used to remove ear wax are uncommon, but may result in discomfort, irritation, or pain. [5] Antibiotic ear drops may cause ear discomfort, pain, or itching. [ 1 ] When cold ear drops are used, it may cause brief but severe dizziness and/or vertigo.