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  2. Cash on delivery - Wikipedia

    en.wikipedia.org/wiki/Cash_on_delivery

    A British cash on delivery registered letter from 1940s London showing 4s 7d due on delivery.. Cash on delivery (COD), sometimes called payment on delivery, [1] cash on demand, payment on demand or collect on delivery [2] is the sale of goods by mail order where payment is made on delivery rather than in advance.

  3. Tramadol - Wikipedia

    en.wikipedia.org/wiki/Tramadol

    Tramadol, sold under the brand name Ultram among others, [1] is an opioid pain medication and a serotonin–norepinephrine reuptake inhibitor (SNRI) used to treat moderately severe pain. [12] [16] When taken by mouth in an immediate-release formulation, the onset of pain relief usually begins within an hour. [12] It is also available by ...

  4. N,O-Didesmethyltramadol - Wikipedia

    en.wikipedia.org/wiki/N,O-didesmethyltramadol

    N,O-Didesmethyltramadol (tramadol metabolite M5) is an opioid derivative which is one of two active metabolites of the opioid analgesic medication tramadol.It is many times less potent than the other active metabolite O-Desmethyltramadol but is still more potent as a mu opioid receptor agonist than tramadol itself, unlike the other metabolites N-desmethyltramadol, N,N-didesmethyltramadol, and ...

  5. Celecoxib/tramadol - Wikipedia

    en.wikipedia.org/wiki/Celecoxib/tramadol

    Celecoxib/tramadol sold under the brand name Seglentis, is a fixed-dose combination of the anti-inflammatory celecoxib and the opioid tramadol used for the management and treatment of pain. [ 1 ] Developed by Spanish pharmaceutical company Esteve , it was approved for medical use in the United States in October 2021.

  6. Tramadol/paracetamol - Wikipedia

    en.wikipedia.org/wiki/Tramadol/paracetamol

    Tramadol/paracetamol, also known as tramadol/acetaminophen and sold under the brand name Ultracet among others, is a fixed-dose combination medication used for the treatment of moderate to severe pain. [3] [4] It contains tramadol, as the hydrochloride, an analgesic; and paracetamol an analgesic. [3] [4] It is taken by mouth. [3] [4]

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  8. Desmetramadol - Wikipedia

    en.wikipedia.org/wiki/Desmetramadol

    (+)-Desmetramadol is a G-protein biased μ-opioid receptor full agonist. [4] It shows comparatively far lower affinity for the δ-and κ-opioid receptors. [5]The two enantiomers of desmetramadol show quite distinct pharmacological profiles; [6] both (+) and (−)-desmetramadol are inactive as serotonin reuptake inhibitors, [7] but (−)-desmetramadol retains activity as a norepinephrine ...

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    Enjoy a classic game of Hearts and watch out for the Queen of Spades!