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Flunarizine is effective in the prophylaxis of migraine, [2] occlusive peripheral vascular disease, vertigo of central and peripheral origin, [3] and as an add-on in the treatment of epilepsy where its effect is weak and not recommended. [4] It has been shown to significantly reduce headache frequency and severity in both adults and children.
Meclizine, sold under the brand name Bonine, among others, is an antihistamine used to treat motion sickness and dizziness . [3] It is taken by mouth. [3] Effects generally begin in an hour and last for up to a day. [3] Common side effects include sleepiness and dry mouth. [3] Serious side effects may include allergic reactions. [3]
Betahistine, sold under the brand name Serc among others, is an anti-vertigo medication.It is commonly prescribed for balance disorders or to alleviate vertigo symptoms.It was first registered in Europe in 1970 for the treatment of Ménière's disease, but current evidence does not support its efficacy in treating it.
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Cinnarizine is predominantly used to treat nausea and vomiting associated with motion sickness, [6] vertigo, [8] Ménière's disease, [9] or Cogan's syndrome. [3] It is one of only a few drugs that has a beneficial effect in the chronic treatment of the vertigo and tinnitus associated with Ménière's disease.
Benzonatate was first made available in the United States in 1958 as a prescription medication for the treatment of cough in individuals over the age of 10. [ 24 ] [ 25 ] There is a variety of prescription opioid -based cough relievers, such as hydrocodone and codeine , but have unwanted side effects and potential of abuse and diversion. [ 22 ]
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