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She believes that some patients with a type of breast cancer, ductal carcinoma in situ, should be placed on active surveillance instead of undergoing a biopsy, mastectomy or lumpectomy. [9] [10] Dr. Esserman is one of the most vocal proponents of the idea that breast cancer screening brings with it overdiagnosis and overtreatment.
Overdiagnosis has been identified in mammographic screening for breast cancer. [9] [10] Long-term follow-up of the Malmo randomized trial of mammography found a persistent excess of 115 breast cancers in the screened group 15 years after the trial was completed (a 10% rate of overdiagnosis). [11]
Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.
Breast cancer is not a single disease but multiple ones, each carrying varying degrees of risk for endangering women’s health. In recent years, many researchers have been focused on DCIS: ductal ...
The study, which looked at data from 2004 to 2021, found that advanced breast cancer rates have risen among women of all ages, with the sharpest increases in young women aged 20 to 39, and women ...
Breast cancer screening is the medical screening of asymptomatic, ... Consequently, finding and treating many cases of DCIS represents overdiagnosis and overtreatment ...
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