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A 95% confidence level does not mean that 95% of the sample data lie within the confidence interval. A 95% confidence level does not mean that there is a 95% probability of the parameter estimate from a repeat of the experiment falling within the confidence interval computed from a given experiment. [25]
The probability density function (PDF) for the Wilson score interval, plus PDF s at interval bounds. Tail areas are equal. Since the interval is derived by solving from the normal approximation to the binomial, the Wilson score interval ( , + ) has the property of being guaranteed to obtain the same result as the equivalent z-test or chi-squared test.
In the social sciences, a result may be considered statistically significant if its confidence level is of the order of a two-sigma effect (95%), while in particle physics and astrophysics, there is a convention of requiring statistical significance of a five-sigma effect (99.99994% confidence) to qualify as a discovery. [3]
To calculate these confidence intervals, all that is required is an independently and identically distributed (iid) sample from the distribution and known bounds on the support of the distribution. The latter requirement simply means that all the nonzero probability mass of the distribution must be contained in some known interval [ a , b ...
The rule can then be derived [2] either from the Poisson approximation to the binomial distribution, or from the formula (1−p) n for the probability of zero events in the binomial distribution. In the latter case, the edge of the confidence interval is given by Pr( X = 0) = 0.05 and hence (1− p ) n = .05 so n ln (1– p ) = ln .05 ≈ −2.996.
Fieller, EC (1944). "A fundamental formula in the statistics of biological assay, and some applications". Quarterly Journal of Pharmacy and Pharmacology. 17: 117–123. Motulsky, Harvey (1995) Intuitive Biostatistics. Oxford University Press. ISBN 0-19-508607-4; Senn, Steven (2007) Statistical Issues in Drug Development. Second Edition. Wiley.
For a confidence level, there is a corresponding confidence interval about the mean , that is, the interval [, +] within which values of should fall with probability . Precise values of z γ {\displaystyle z_{\gamma }} are given by the quantile function of the normal distribution (which the 68–95–99.7 rule approximates).
A confidence interval states there is a 100γ% confidence that the parameter of interest is within a lower and upper bound. A common misconception of confidence intervals is 100γ% of the data set fits within or above/below the bounds, this is referred to as a tolerance interval, which is discussed below.