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In equation above, positive post-test probability is calculated using the likelihood ratio positive, and the negative post-test probability is calculated using the likelihood ratio negative. Odds are converted to probabilities as follows: [18]
The positive predictive value (PPV), or precision, is defined as = + = where a "true positive" is the event that the test makes a positive prediction, and the subject has a positive result under the gold standard, and a "false positive" is the event that the test makes a positive prediction, and the subject has a negative result under the gold standard.
Diagram relating pre- and post-test probabilities, with the green curve (upper left half) representing a positive test, and the red curve (lower right half) representing a negative test, for the case of 90% sensitivity and 90% specificity, corresponding to a likelihood ratio positive of 9, and a likelihood ratio negative of 0.111.
Despite the fact that the likelihood ratio in favor of the alternative hypothesis over the null is close to 100, if the hypothesis was implausible, with a prior probability of a real effect being 0.1, even the observation of p = 0.001 would have a false positive rate of 8 percent. It wouldn't even reach the 5 percent level.
In medical testing with binary classification, the diagnostic odds ratio (DOR) is a measure of the effectiveness of a diagnostic test. [1] It is defined as the ratio of the odds of the test being positive if the subject has a disease relative to the odds of the test being positive if the subject does not have the disease.
In statistics, the likelihood-ratio test is a hypothesis test that involves comparing the goodness of fit of two competing statistical models, typically one found by maximization over the entire parameter space and another found after imposing some constraint, based on the ratio of their likelihoods.
The likelihood ratio is central to likelihoodist statistics: the law of likelihood states that degree to which data (considered as evidence) supports one parameter value versus another is measured by the likelihood ratio. In frequentist inference, the likelihood ratio is the basis for a test statistic, the so-called likelihood-ratio test.
Given a model, likelihood intervals can be compared to confidence intervals. If θ is a single real parameter, then under certain conditions, a 14.65% likelihood interval (about 1:7 likelihood) for θ will be the same as a 95% confidence interval (19/20 coverage probability).