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Tetracyclic antidepressants (TeCAs) are a class of antidepressants that were first introduced in the 1970s. They are named after their tetracyclic chemical structure , containing four rings of atoms , and are closely related to the tricyclic antidepressants (TCAs), which contain three rings of atoms.
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification. Chemical/generic names are listed first, with brand names in parentheses.
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Jason Statham (/ ˈ s t eɪ θ əm / STAY-thəm; born 26 July 1967) is an English actor and producer. He is known for portraying tough, gritty, or violent characters in various action thriller films, and has been credited for leading the resurgence of action films during the 2000s and 2010s. [ 1 ]
Mirtazapine, a tetracyclic antidepressant. Tetracyclics are cyclic chemical compounds that contain four fused rings of atoms, for example, Tröger's base . Some tricyclic compounds having three fused and one tethered ring (connected to main nucleus by a single bond) can also classified as tetracyclic, for example, ciclazindol .
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Mianserin is a tetracyclic piperazinoazepine. Mirtazapine was developed by the same team of organic chemists and differs via addition of a nitrogen atom in one of the rings. [ 43 ] [ 44 ] ( S )-(+)-Mianserin is approximately 200–300 times more active than its enantiomer ( R )-(−)-mianserin; hence, the activity of mianserin lies in the ( S ...
Amoxapine, sold under the brand name Asendin among others, is a tricyclic antidepressant (TCA). It is the N-demethylated metabolite of loxapine.Amoxapine first received marketing approval in the United States in 1980, approximately 10 to 20 years after most of the other TCAs were introduced in the United States.