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The olfactory mucosa is the neuroepithelial mucosa [1] lining the roof and upper parts of the septum and lateral wall of the nasal cavity [1] [2] which contains bipolar neurons of the primary receptor neurons of the olfactory pathway, as well as supporting cells.
Anosmia may very occasionally be an early sign of a degenerative brain disease such as Parkinson's disease and Alzheimer's disease. [22] Another specific cause of permanent loss could be from damage to olfactory receptor neurons because of use of certain types of nasal spray; i.e., those that cause vasoconstriction of the nasal microcirculation ...
Zinc toxicity is a medical condition involving an overdose on, or toxic overexposure to, zinc. Such toxicity levels have been seen to occur at ingestion of greater than 50 mg of zinc. [1] [unreliable medical source?] Excessive absorption of zinc can suppress copper and iron absorption. The free zinc ion in solution is highly toxic to bacteria ...
People with Type 2 diabetes and certain gastrointestinal disorders, such as Crohn’s disease or colitis, as well as those who have had bariatric surgery, may be also at risk of zinc deficiency.
Side effects may include abdominal pain, vomiting, headache, and feeling tired. [2] While normal doses are deemed safe in pregnancy and breastfeeding, the safety of larger doses is unclear. [3] Greater care should be taken in those with kidney problems. [2] Zinc is an essential mineral in people as well as other animals. [4]
You need zinc to function properly, but in order for it to work, you need to take it at the right time. Here, experts explain when to take zinc.
The underlying cause is due to the defective migration of GNRH neurons from olfactory placode to hypothalamus, leading to congenital GNRH deficiency. This leads to olfactory problems such as anosmia, optic defects like color blindness, and results in hypothalmic deficiencies associated with low levels of LH, affecting sex hormone testosterone in males or estrogen and progesterone in females.
Neurologists have observed that olfactory dysfunction is a cardinal feature of several neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. Most of these patients are unaware of an olfactory deficit until after testing where 85% to 90% of early-stage patients showed decreased activity in central odor processing ...