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  2. Antinuclear antibody - Wikipedia

    en.wikipedia.org/wiki/Antinuclear_antibody

    An ANA test is considered positive if fluorescence is seen at a titre of 1:40/1:80. Higher titres are more clinically significant as low positives (≤1:160) are found in up to 20% of healthy individuals, especially the elderly. Only around 5% of the healthy population have ANA titres of 1:160 or higher. [8] [53]

  3. Anti-dsDNA antibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-dsDNA_antibodies

    Flow cytometry for the detection of ANA uses multiplexed polystyrene beads coated with multiple autoantigens, such as SSA, SSB, Sm, RNP, Scl-70, Jo-1, dsDNA, centromere B and histone. Serum is incubated with the beads and in the presence of anti-dsDNA antibodies, or any other ANA, the antibodies will bind and fluorescent labelled secondary ...

  4. Anti-neutrophil cytoplasmic antibody - Wikipedia

    en.wikipedia.org/wiki/Anti-neutrophil_cytoplasm...

    Immunofluorescence (IF) on ethanol-fixed neutrophils is used to detect ANCA, although formalin-fixed neutrophils may be used to help differentiate ANCA patterns. ANCA can be divided into four patterns when visualised by IF; cytoplasmic ANCA (c-ANCA), C-ANCA (atypical), perinuclear ANCA (p-ANCA) and atypical ANCA (a-ANCA), also known as x-ANCA. c-ANCA shows cytoplasmic granular fluorescence ...

  5. Autoantibody - Wikipedia

    en.wikipedia.org/wiki/Autoantibody

    ANA is a marker of the autoimmune process – it is positive with a variety of different autoimmune diseases but not specific. Consequently, if an ANA test is positive, it is often followed up with other tests associated with arthritis and inflammation , such as a rheumatoid factor (RF), an erythrocyte sedimentation rate (ESR), a c-reactive ...

  6. Why you have COVID symptoms and a negative test: You ... - AOL

    www.aol.com/finance/why-covid-symptoms-negative...

    If you test negative using an at-home test, repeat the test again in 48 hours. If you were exposed to COVID, test at least 5 full days after exposure. If you still test negative, wait 48 more ...

  7. Undifferentiated connective tissue disease - Wikipedia

    en.wikipedia.org/wiki/Undifferentiated...

    Patients with UCTD usually have positive ANA (antinuclear antibody), and raised ESR (erythrocyte sedimentation rate) values, without typical autoantibody specificities. [14] Some 20% of the general population, [ 15 ] and up to 15% of completely healthy people, [ 16 ] test positive for ANA, but nonetheless this is regarded by some as almost ...

  8. Got a Faint Line on a COVID-19 Home Test? Here's What It Means

    www.aol.com/got-faint-line-covid-19-145700240.html

    A false positive isn't as likely as a false negative result on a home test early in a person's infection, explains Sandra H. Bonat, M.D., a pediatric expert and virologist with VIP StarNetwork, a ...

  9. Hook effect - Wikipedia

    en.wikipedia.org/wiki/Hook_effect

    Since the antibodies do not bridge between antigens, no agglutination occurs. Because no agglutination occurs, the test is interpreted as negative. In this case, the result is a false negative. The range of relatively high antibody concentrations within which no reaction occurs is called the prozone. [5]

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