Ad
related to: cefoperazone sulbactam vs meropenem 20 15 12 60 tablets- 109 S High St #100, Columbus, OH · Directions · (614) 224-4261
GoodRx helps people pay for Rx they otherwise couldn't afford. - Patch
- How GoodRx® Works
Get Rx Coupons, Save Up to 80%
No Commitment & No Fees
- GoodRx® Blog
Get the Latest Healthcare News
Find What Matters Most to You
- Flu Shot & Med Discounts
Get a Free Discount for Your
Flu Shot or Prescriptions
- Do I Need Insurance?
No! Compare Our Prices to Your
Insurance & Get the Biggest Savings
- How GoodRx® Works
Search results
Results from the WOW.Com Content Network
Cefoperazone/sulbactam is a combination drug used as an antibiotic. It is effective for the treatment of urinary tract infections . [ 2 ] It contains cefoperazone , a β-lactam antibiotic , and sulbactam , a β-lactamase inhibitor , which helps prevent bacteria from breaking down cefoperazone.
Cefoperazone [Unlike most third-generation agents, cefoperazone is active against Pseudomonas aeruginosa], combination Cefoperazone with Sulbactam makes more effective antibiotic, because Sulbactam avoid degeneration of Cefoperazone: Cefobid (discontinued) Cefotaxime: Claforan: Cefpodoxime: Vantin, Banadoz
Cefoperazone contains an N-methylthiotetrazole (NMTT or 1-MTT) side chain.As the antibiotic is broken down in the body, it releases free NMTT, which can cause hypoprothrombinemia (likely due to inhibition of the enzyme vitamin K epoxide reductase) and a reaction with ethanol similar to that produced by disulfiram (Antabuse effect), due to inhibition of aldehyde dehydrogenase.
[12] [13] [14] While β-lactam ring in meropenem is more accessible to water molecules than in the other β-lactam antibiotics, that facilitates the hydrolysis process and faster degradation of meropenem's antibacterial properties in aqueous solutions, it is more resistant to degradation by β-lactamase enzymes produced by bacteria than the ...
The β-lactam core structures. (A) A penam.(B) A carbapenam.(C) An oxapenam.(D) A penem.(E) A carbapenem.(F) A monobactam.(G) A cephem.(H) A carbacephem.(I) An oxacephem. This is a list of common β-lactam antibiotics—both administered drugs and those not in clinical use—organized by structural class.
Sulbactam is a β-lactamase inhibitor. This drug is given in combination with β-lactam antibiotics to inhibit β-lactamase , an enzyme produced by bacteria that destroys the antibiotics . [ 1 ]
Vaborbactam is a boronic acid β-lactamase inhibitor with a high affinity for serine β-lactamases, including Klebsiella pneumoniae carbapenemase (KPC). [5] Vaborbactam inhibits a variety of β-lactamases, exhibiting a 69 nM K i against the KPC-2 carbapenemase and even lower inhibition constants against CTX-M-15 and SHV-12.
Cefixime, sold under the brand name Suprax among others, is an antibiotic medication used to treat a number of bacterial infections. [5] These infections include otitis media, strep throat, pneumonia, urinary tract infections, gonorrhea, and Lyme disease. [5]
Ad
related to: cefoperazone sulbactam vs meropenem 20 15 12 60 tablets- 109 S High St #100, Columbus, OH · Directions · (614) 224-4261
GoodRx helps people pay for Rx they otherwise couldn't afford. - Patch