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Heme is a vital molecule for all of the body's organs. It is a component of hemoglobin, the molecule that carries oxygen in the blood. Hepatoerythropoietic porphyria has been described as a homozygous form of porphyria cutanea tarda, [2] although it can also be caused if two different mutations occur at the same locus.
There have been many different theories regarding the causes of excoriation disorder, including biological and environmental factors. [10]A common hypothesis is that excoriation disorder is often a coping mechanism to deal with elevated levels of turmoil, boredom, anxiety, or stress within the individual, and that the individual has an impaired stress response.
Toxic shock syndrome (TSS) is a condition caused by bacterial toxins. [1] Symptoms may include fever, rash, skin peeling, and low blood pressure. [1] There may also be symptoms related to the specific underlying infection such as mastitis, osteomyelitis, necrotising fasciitis, or pneumonia.
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In older patients, emotional instability may be less evident, or depression may occur, and the symptoms and signs are manifestly circulatory. In many, the thyroid is not readily palpable. [4] Symptoms such as rapid heart rate, shortness of breath on exertion, and edema may predominate. Older patients also tend to have more weight loss and less ...
Alcoholic polyneuropathy usually has a gradual onset over months or even years, although axonal degeneration often begins before an individual experiences any symptoms. [2] The disease typically involves sensory issues and motor loss, as well as painful physical perceptions, though all sensory modalities may be involved. [3]
Diagnosis is based on symptoms, supported by a skin biopsy or blood tests. [6] While no cure is known, treatment may improve symptoms. [2] Medications used include corticosteroids, methotrexate, and non-steroidal anti-inflammatory drugs (NSAIDs). [2] Outcome depends on the extent of disease. [3]
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