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Guidelines on the choice of agents and how best to step up treatment for various subgroups in hypertension (high blood pressure) have changed over time and differ between countries. A Comparison of International Guidelines on Goal Blood Pressure and Initial Therapy for Adults With Hypertension (adapted from JNC 8 guidelines [ 1 ] )
The American Heart Association and the American College of Cardiology issued guidelines on November 13, 2017, based on the findings of the Systolic Blood Pressure Intervention Trial (SPRINT) a large randomized trial published in November 2015 looking at systolic blood pressure targets of 140 and 120 mmHg among persons with at least 130 mmHg ...
This makes it easier to use the inhaler and helps ensure that more of the medication gets into the lungs instead of just into the mouth or the air. Proper use of a spacer can make an inhaler more effective in delivering medicine. [9] Spacers can be especially helpful to adults and children who find a regular metered dose inhaler hard to use.
Pulmonary drug delivery is a route of administration in which patients use an inhaler to inhale their medications and drugs are absorbed into the bloodstream via the lung mucous membrane. This technique is most commonly used in the treatment of lung diseases, for example, asthma and chronic obstructive pulmonary disease (COPD).
Treatment of pulmonary hypertension is determined by whether the PH is arterial, venous, hypoxic, thromboembolic, or miscellaneous. If it is caused by left heart disease, the treatment is to optimize left ventricular function by the use of medication or to repair/replace the mitral valve or aortic valve . [ 68 ]
In 2018, the American Heart Association and American College of Cardiology issued new guidelines for clinicians on the management of cholesterol as a way to reduce risk for heart attack and stroke. Newly included in the guidelines is a recommendation to use coronary artery calcium score if healthcare providers are having difficulty deciding if ...
Beyond use in chronic lung disease, nebulizers may also be used to treat acute issues like the inhalation of toxic substances. One such example is the treatment of inhalation of toxic hydrofluoric acid (HF) vapors. [8] Calcium gluconate is a first-line treatment for HF exposure to the skin. By using a nebulizer, calcium gluconate is delivered ...
DPIs are an alternative to the aerosol-based inhalers commonly called metered-dose inhaler (or MDI). The DPIs may require some procedure to allow a measured dose of powder to be ready for the patient to take. The medication is commonly held either in a capsule for manual loading or in a proprietary form inside the inhaler.