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  2. Presumptive and confirmatory tests - Wikipedia

    en.wikipedia.org/wiki/Presumptive_and...

    Most people who take a drug test take a presumptive test, cheaper and faster than other methods of testing. However, it is less accurate and can render false results. The FDA recommends for confirmatory testing to be conducted and the placing of a warning label on the presumptive drug test: "This assay provides only a preliminary result.

  3. Major adverse cardiovascular events - Wikipedia

    en.wikipedia.org/wiki/Major_adverse...

    The so-called "classical 3-point MACE" is defined as a composite of nonfatal stroke, nonfatal myocardial infarction, and cardiovascular death. [4] [5] Another study similarly defined MACE as a composite of nonfatal stroke, nonfatal acute coronary syndrome, and death from vascular causes. [6]

  4. Diagnosis of myocardial infarction - Wikipedia

    en.wikipedia.org/wiki/Diagnosis_of_myocardial...

    In particular, acute myocardial infarction in the distribution of the circumflex artery is likely to produce a nondiagnostic ECG. [10] The use of additional ECG leads like right-sided leads V3R and V4R and posterior leads V7, V8, and V9 may improve sensitivity for right ventricular and posterior myocardial infarction. [citation needed]

  5. Management of acute coronary syndrome - Wikipedia

    en.wikipedia.org/wiki/Management_of_acute...

    Information card published by the National Heart, Lung, and Blood Institute urging people with symptoms of angina to call the emergency medical services.. Because of the relationship between the duration of myocardial ischemia and the extent of damage to heart muscle, public health services encourage people experiencing possible acute coronary syndrome symptoms or those around them to ...

  6. Coronary thrombosis - Wikipedia

    en.wikipedia.org/wiki/Coronary_thrombosis

    Coronary "microembolization" is being explored as a focal point for coronary thrombus formation and subsequent sudden death due to acute myocardial infarction. [6] High mobility group box-1 (HMGB-1) proteins as important mediators in thrombus formation. [7] Coronary sinus thrombosis as a severe complication after procedures. [8]

  7. Pivotal trial - Wikipedia

    en.wikipedia.org/wiki/Pivotal_trial

    A pivotal trial is typically a Phase III clinical trial in the multi-year process of clinical research intended to demonstrate and confirm the safety and efficacy of a treatment – such as a drug candidate, medical device or clinical diagnostic procedure – and to estimate the incidence of common adverse effects. [1]

  8. Instantaneous wave-free ratio - Wikipedia

    en.wikipedia.org/wiki/Instantaneous_wave-free_ratio

    The instantaneous wave-free ratio (iFR, sometimes referred to as the instant wave-free ratio or instant flow reserve) is a diagnostic tool used to assess whether a stenosis is causing a limitation of blood flow in coronary arteries with subsequent ischemia. iFR is performed during cardiac catheterisation (angiography) using invasive coronary pressure wires which are placed in the coronary ...

  9. Vulnerable plaque - Wikipedia

    en.wikipedia.org/wiki/Vulnerable_plaque

    In case of a vulnerable plaque, this results in a larger diameter of the Artery Lumen, which means that patient's life style is not affected, however, when the thin fibrous cap breaks, this causes a prompt activation of platelets which causes the occlusion of the artery, which causes a sudden heart attack if it occurs in the coronary artery.