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Proton-pump inhibitors have largely superseded the H 2-receptor antagonists, a group of medications with similar effects but a different mode of action, and heavy use of antacids. [3] A potassium-competitive acid blocker (PCAB) revaprazan was marketed in Korea as an alternative to a PPI.
Most oral PPI preparations are enteric-coated, due to the rapid degradation of the drugs in the acidic conditions of the stomach. For example omeprazole is unstable in acid with a half-life of 2 min at pH 1–3, but is significantly more stable at pH 7 (half-life ca. 20 h).
Tirzepatide [12] is an antidiabetic medication used to treat type 2 diabetes [9] [13] [14] [15] and for weight loss. [10] [16] Tirzepatide is administered via subcutaneous injections (under the skin).
[28]: 130 Wyeth licensed the US patent from Altana, [29] and obtained marketing approval from the US FDA in 2000 under the trade name Protonix. [30] [31] In 2004, worldwide sales of the drug were $3.65 billion, about half of which were in the US. [29] In 2007, Altana's drug business was acquired by Nycomed. [32]
The Juvenile Diabetes Cure Alliance (JDCA) is a registered 501(c)(3) non-profit organization dedicated to developing a Practical Cure for type 1 diabetes.The organization advocates for increasing type 1 diabetes cure research and publishes reports on a variety of related topics, including research progress, fundraising utilization, and donor priorities.
Richard K. Bernstein (born June 17, 1934) is a physician and an advocate for a low-carbohydrate diabetes diet to help achieve normal blood sugars for diabetics. Bernstein has type 1 diabetes . His private medical practice in Mamaroneck, New York is devoted solely to treating diabetes and prediabetes.
Novo Nordisk works with doctors, nurses, and patients, to develop products for self-managing diabetes conditions. The DAWN (Diabetes Attitudes, Wishes and Needs) 2001 study was a global survey of the psychosocial aspects of living with diabetes. It involved over 5,000 people with diabetes and almost 4,000 care providers. [56]
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