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The process of spermatogenesis as the cells progress from primary spermatocytes, to secondary spermatocytes, to spermatids, to Sperm Cycle of the seminiferous epithelium of the testis. Spermatocytogenesis is the male form of gametocytogenesis and results in the formation of spermatocytes possessing half the normal complement of genetic material.
Irradiation of male mice during late spermatogenesis can induce damage that persists for at least 7 days in the fertilizing sperm cells, and disruption of maternal DNA double-strand break repair pathways increases sperm cell-derived chromosomal aberrations. [21]
Most recently, the environmental effects on spermatogenesis have become a focus as male infertility in men has become more prevalent. [ 17 ] An important discovery in the spermatogenesis process was the identification of the seminiferous epithelial cycle in mammals—work by C.P. Leblound and Y. Clermont in 1952 that studied the spermatogonia ...
Spermatogenesis, the process for producing spermatozoa, takes place in the seminiferous tubules. During spermatogenesis, the DNA of spermatogenic cells in the seminiferous tubules is subject to damage from such sources as reactive oxygen species. [1] The genomic integrity of spermatogenic cells is protected by DNA repair processes. [2]
Spermatocytogenesis is the male form of gametocytogenesis and involves stem cells dividing to replace themselves and to produce a population of cells destined to become mature sperm. The stem cells involved are called spermatogonia and are a specific type of stem cell known as gametogonia .
Spermiogenesis is the final stage of spermatogenesis, during which the spermatids develop into mature spermatozoa. At the beginning of the stage, the spermatid is a more or less circular cell containing a nucleus , Golgi apparatus , centriole and mitochondria ; by the end of the process, it has radically transformed into an elongated ...
The male reproductive system contains two main divisions: the testicles where sperm are produced, and the penis where semen is ejaculated through the urethra. In humans, both of these organs are outside the abdominal cavity. Having the testicles outside the abdomen facilitates temperature regulation of the sperm, which require specific ...
Anisogamy is the form of sexual reproduction that involves the union or fusion of two gametes which differ in size and/or form. [12] The smaller gamete is considered to be male (a sperm cell), whereas the larger gamete is regarded as female (typically an egg cell, if non-motile).