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Spironolactone is an acne treatment prescribed by dermatologists. Find out how spironolactone improves the appearance of hormonal acne, side effects, and more. Everything I Wish I Knew About ...
According to a study in JAMA Dermatology, the prescribing rates of spironolactone for acne in women rose about 300% from 2017 to 2020.
There are also several oral contraceptives that are also FDA-approved to treat hormonal acne and are sometimes prescribed in conjunction with spironolactone. They work by regulating your hormones ...
Side effects often could not be unambiguously attributed to spironolactone due concomitant use of other medications, particularly birth control pills. Hyperkalemia was rare (14/469; 3.0%) and was "invariably mild and clinically insignificant". Risk of bias was high and quality of evidence was low to very low. Sources: [1]
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Spironolactone may be more effective than birth control pills in the treatment of acne, and the combination of spironolactone with a birth control pill may have greater effectiveness for acne than either alone. [85] In addition, some clinical research has found that flutamide is more effective than spironolactone in the treatment of acne. [64]
Spironolactone blocks your sensitive receptors from your androgens (aka the "male" sex hormones), which helps reduce oil and acne. It's a once-a-day treatment that's typically super effective ...
Unlike spironolactone, bicalutamide has no antimineralocorticoid activity, [97] and for this reason, has no risk of hyperkalemia (which can, rarely/in severe cases, result in hospitalization or death) [112] or other antimineralocorticoid side effects such as urinary frequency, dehydration, hypotension, hyponatremia, metabolic acidosis, or ...
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